Registration Dossier
Registration Dossier
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EC number: 221-576-1 | CAS number: 3148-73-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50>100 mg/L, 48h, daphnia magna, similar to OECD 202, Hutchings 2004
Key value for chemical safety assessment
Additional information
The acute aquatic toxicity of the test substance to Daphnia magna was tested in a non-GLP study for a period of 48 hours. Two test vessels were prepared as a control of reconstituted water containing no test substance and two test vessels were prepared for each of the nominal test concentrations of 0.01, 0.1, 1.0, 10 and 100 mg/L. Five water fleas were randomly assigned to each of the control or test vessels. Animals were not fed during the course of the study and were kept at 20 °C ± 1 °C. No immobilisation of animals was observed at time points of 24 hours and 48 hours of exposure up to the highest nominal test concentration of 100 mg/L and the EC50 value after 48 hours hence is greater than 100 mg/L. No adverse effects were reported up to the nominal test concentration of 100 mg/L and the NOEC value after 48 hours hence is 100 mg/L.
The available data is considered relevant, but not to be reliable or adequate for risk assessment or classification and labelling purposes. This endpoint is not considered complete or conclusive.
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