Registration Dossier
Registration Dossier
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EC number: 237-926-1 | CAS number: 14073-97-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The experimental 48-hour EC50 value based on immobilisation of daphnids was 30.6 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 30.6 mg/L
Additional information
The effects of the test item L-menthan-3-one (CAS 14073-97-3) to daphnids (Daphnia magna) were investigated according to the EU Method C.2 (1992) under GLP conditions (Caspers & Müller 2000). The test item is accompanied by its 2R,5R menthone stereoisomer (CAS 1196-31-2) and fits in the composition profile of the submission item and the study is considered as reliable. The test organisms were exposed under static conditions in closed vessels to nominal concentrations of 0, 6.3, 12.5, 25, 50 and 100 mg/L for 48 hours. The doses were verified by analysis of the TOC and found sufficiently constant under the test conditions. As the recovery was below 80% the effects were assigned to measured concentrations. The 48-hour EC50 was calculated by Probit analysis to be 30.6 mg/L.
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