Registration Dossier
Registration Dossier
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EC number: 208-235-2 | CAS number: 517-23-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 320 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 3.4
- Conclusions:
- A water solubility of 320 g/L was determined for the test item at 20°C.
- Executive summary:
The water solubility of the test item was determined at 20°C according to the "flask method" described in the European Commission Council regulation (EC) No 440/2008, Annex, Part A, A.6., OECD-guideline 105 and the EPA Product Properties Test Guideline OCSPP 830.7840.
Approx. 5 g of distilled water were added to three individual sample weights of approx. 5 g of the test item and stirred at 30°C for different time intervals (26, 50 and 73 h). When stirring was stopped the liquid test item formed a clear separated layer below the aqueous phase. After equilibration (minimum 24 h at 20°C) aliquots of the supernatant saturated aqueous phases were separated from the test item carefully.
A water solubility of 320 g/L was determined for the test item at 20°C.
Reference
Description of key information
The water solubility of the test item was determined at 20°C according to the "flask method" described in the European Commission Council regulation (EC) No 440/2008, Annex, Part A, A.6.,
Approx. 5 g of distilled water were added to three individual sample weights of approx. 5 g of the test item and stirred at 30°C for different time intervals (26, 50 and 73 h). When stirring was stopped the liquid test item formed a clear separated layer below the aqueous phase. After equilibration (minimum 24 h at 20°C) aliquots of the supernatant saturated aqueous phases were separated from the test item carefully.
A water solubility of 320 g/L was determined for the test item at 20°C.
Key value for chemical safety assessment
- Water solubility:
- 320 g/L
- at the temperature of:
- 20 °C
Additional information
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