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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 200-983-8 | CAS number: 76-74-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
4.1 Description of first aid measures
General information: First aider: Pay attention to self-protection!
Inhalation: Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin contact: Wash off with plenty of water and soap for at least 15 minutes. Remove contaminated clothing and shoes. If irritation occurs or persists, get medical attention. Wash clothing and shoes before reuse.
In case of eye contact: After contact with the eyes, rinse with water with the eyelids open for a sufficient length of time, then consult an ophthalmologist immediately.
In case of ingestion: Call a physician immediately.
4.2 Most important symptoms and effects, both acute and delayed
Prolonged or repeated exposure can lead to habituation or addiction.
May increase toxic effects: Respiratory depression and sedation, Gastrointestinal disturbances. Overexposure may cause reproductive disorders based on tests with laboratory animals.
Continued use of barbiturates, even in therapeutic doses, may result in psychic or physical dependence. Abrupt withdrawal of the drug may result in a severe abstinence syndrome which includes grand mal seizures and delirium.
4.3 Indication of immediate medical attention and special treatment needed
When symptoms suggesting toxicity, immediate medical treatment necessary. If possible, show this data sheet.
Fire-fighting measures
5.1 Extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
5.2 Special hazards arising from the substance or mixture
In case of fire may be liberated: Carbon monoxide (CO), Nitrogen oxides (NOx).
5.3 Precautions for fire-fighters
Do not inhale explosion and combustion gases.
5.4 Further information
Contaminated fire extinguishing water must collect separately. It must not be discharged into drains.
Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Avoid generation of dust. Wear personal protection equipment. Wear breathing apparatus if exposed to vapours/dusts.
6.2 Environmental precautions
Do not allow to enter drains/surface water/ground-water.
6.3 Methods and materials for containment and cleaning up
Carefully take up dry. Vacuum residues. The material collected according to the section Disposal.
Handling and storage
7.1 Precautions for safe handling
All work processes must always be designed so that the following is as low as possible: Inhalation, Skin contact, Eye contact. Avoid generation of dust. The product is combustible and dust explosive.
The substance is registered under the Regulation EG1907/2006 (REACH) as a transported isolated intermediate; the use must be complied with the conditions in Article 18 (4).
7.2 Conditions for safe storage, including any incompatibilities
Provide adequate ventilation as well as local exhaustion at critical locations.
Keep container tightly closed and in a well-ventilated place. Do not store at temperatures above 30 °C.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
- Chemical name:
- Pentobarbital
- Labels:
- 6.1
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
- Chemical name:
- Pentobarbital
- Labels:
- 6.1
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
- Chemical name:
- Pentobarbital
- Labels:
- 6.1
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- TOXIC SOLID, ORGANIC, N.O.S.
- Chemical name:
- Pentobarbital
- Labels:
- 6.1
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
8.1 Control parameters
Limits for occupational safety are not be valid, because the substance must be used in closed system according to Article 18 (4) REACH. Exposures are therefore minimized.
8.2 Exposure controls
Appropriate engineering controls:
Immediately change contaminated clothing. Wash thoroughly after handling. General room ventilation is adequate unless the process generates dust or fumes. Work clothing should be removed in a change room on site and laundered professionally. Employees should shower and change into street clothes before leaving the facility. Prevent the accumulation of dust in the work area by thorough periodic cleaning of the area.
Personal protective equipment:
Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection: Is required whenever air contamination (dust, mist, or vapors) is generated by the process. A NIOSH-approved high efficiency toxic dust/mist/fume respirator is recommended.
Eye protection: required
Hand protection: In full and splash contact:
Glove material: PVC, Butyl-/Nitrile rubber
Layer thickness: 0.11 mm
The protective gloves to be used must comply with the specifications of EC directive 89/686/EEC and the resultant standard EN374.
This recommendation applies only to the product stated in the safe data sheet and supplied by us as well as to the purpose specified by us. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves.
Stability and reactivity
10.1 Reactivity
No special conditions
10.2 Chemical stability
Stable under normal conditions
10.3 Possibility of hazardous reactions
Oxidizing agents
10.4 Conditions to avoid
Light, Moisture (weak hygroscopic)
10.5 Incompatible materials
Bases
Disposal considerations
13.1 Waste treatment methods
Product:
Product waste and residues must be disposed of according to current laws.
Packaging:
Non-contaminated packages may be recycled. Handle contaminated packaging in the same way as the substance itself.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.