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EC number: 231-193-1 | CAS number: 7446-07-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
- Endpoint:
- fish early-life stage toxicity
- Type of information:
- experimental study planned (based on read-across)
- Remarks:
- ECHA decision on testing proposal TPE-D-2114577079-36-01/F
- Justification for type of information:
- - Name of the substance on which testing is proposed to be carried out: sodium tellurite (IV)
- Name of the substance for which the testing proposal will be used: tellurium dioxide
Tellurium dioxide is relatively poorly water soluble. Underlying the basic assumption that effects caused by the bioavailable metal fraction and the same toxicokinetic behaviour, ecotoxicity data from higher soluble tellurium compound were considered appropriate for the ecotoxicity assessment of tellurium.
Based on the results of a transformation dissolution screening and determination of the dissolved element concentrations, we may conclude that dissolved tellurium dioxide is predominantly available as Te(IV). Sodium tellurite (IV) is therefore considered an adequate testing material for OECD 210 and for read-across to tellurium dioxide.
Cross-reference
- Reason / purpose for cross-reference:
- read-across: supporting information
Reference
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2022
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 29 Guidance Document on Transformation/Dissolution of Metals and Metal Compounds in Aqueous Media.
- Version / remarks:
- July 2001
- GLP compliance:
- yes
- Specific details on test material used for the study:
- sodium tellurate (VI) and sodium tellurite (IV) have been used as standards to identify dissolved tellurium species
- Conclusions:
- During this study on Tellurium dioxide at a loading of 100 mg/L, it was shown that:
• For total tellurium, an average concentration of 0.383 mg/L Tetotal (CVoverall = 33 %; N = 9) was measured at pH 6 (i.e. 0.48 % total tellurium release) and 1.80 mg/L Tetotal (CVoverall = 13 %; N = 9) at pH 8 (i.e. 2.3 % total tellurium release),
• For tellurium(IV), an average concentration of 0.389 mg/L Te(IV) (CVoverall = 33 %; N = 9) was measured at pH 6 (i.e. 0.49 % tellurium(IV) release) and 1.79 mg/L Te(IV) (CVoverall = 13 %; N = 9) at pH 8 (i.e. 2.2 % tellurium(IV) release),
• For tellurium(VI), an average concentration of <0.002 mg/L Te(VI) (N = 9) was measured at pH 6 (i.e. <0.003 % tellurium(VI) release) and 0.002 mg/L Te(VI) (CVoverall = 24 %; N = 9) at pH 8 (i.e. 0.003 % tellurium(VI) release),
after 24 hours of exposure to the test medium at pH 6 and 8, respectively.
Based on the rounded results of the dissolved element concentrations, we may conclude that nominal “pH 8” is the pH where the highest dissolved tellurium concentrations, available as Te(IV), were measured. Only traces of Te(VI) could be detected.
For the test at nominal pH 6 at a loading of 100 mg/L Tellurium dioxide, average dissolved concentrations of:
• 0.383 ± 0.125 mg/L Tetotal (CVoverall = 33 %; N = 9),
• 0.389 ± 0.129 mg/L Te(IV) (CVoverall = 33 %; N = 9),
• <0.002 mg/L Te(VI) (N = 9),
were found at the 24 hours endpoint.
Based on the tellurium content in the test item and the average dissolved concentrations in the test solutions:
• a release of tellurium of 0.48 % of the content,
• a release of tellurium(IV) of 0.49 % of the content,
• a release of tellurium(VI) of <0.003 % of the content,
could be calculated at the 24 hours endpoint in test medium at pH 6.
For the test at nominal pH 8 at a loading of 100 mg/L Tellurium dioxide, average dissolved concentrations of:
• 1.80 ± 0.23 mg/L Tetotal (CVoverall = 13 %; N = 9),
• 1.79 ± 0.24 mg/L Te(IV) (CVoverall = 13 %; N = 9),
• 0.002 ± 0.001 mg/L Te(VI) (CVoverall = 24 %; N = 9),
were found at the 24 hours endpoint.
Based on the tellurium content in the test item and the average dissolved concentrations in the test solutions:
• a release of tellurium of 2.3 % of the content,
• a release of tellurium(IV) of 2.2 % of the content,
• a release of tellurium(VI) of 0.003 % of the content,
could be calculated at the 24 hours endpoint in test medium at pH 8.
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)
Test material
- Reference substance name:
- sodium tellurite
- Cas Number:
- 10102-20-2
- Molecular formula:
- Na2O3Te
- IUPAC Name:
- sodium tellurite
Constituent 1
Results and discussion
Applicant's summary and conclusion
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