Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 801-093-8 | CAS number: 1315251-11-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
An OECD TG 222 study in compliance with GLP criteria with Earthworm (Eisenia andrei) is available for the substance. Groups of 10 earthworms per replicate (40 per concentration for test item treatments and 80 per control) were exposed to nominal concentrations of 1.00, 3.00, 9.00, 27.0, 90.0, 270, and 520 mg/kg soil dw for 56 days in a laboratory study with artificial soil. The test condition was maintained at 18 - 22 °C, 51.7 – 56.8% maximum water holding capacity and 16 hours light and 8 hours darkness light cycle (400 lux to 800 lux light intensity). The adult earthworm mortality, behavioural effects and biomass development was studied after 28 days exposure. Moreover, the reproduction rate (number of offspring) was assessed after additional 28 days (assessed 56 days after application).
A mortality of 12.5% and 97.5% was found at the test concentrations of 270 and 520 mg test item/kg soil dw, respectively, which was statistically significantly different compared to the control, where 0% of the earthworms died. The body weight changes of the earthworms after 4 weeks exposure to the substance were not statistically significantly different compared to the control up to and including the test concentration of 90.0 mg test item/kg soil dw. At the test concentration of 270 mg test item/kg soil dw and above the body weight changes of the earthworms were statistically significantly reduced compared to the control. The reproduction rates were not statistically significantly different compared to the control up to and including the test concentration of 9.00 mg test item/kg soil dw. At the test concentration of 27.0 mg test item/kg soil dw and above, reproduction was statistically significantly reduced compared to the control. No behavioural abnormalities were observed in any of the treatment groups. The feeding activity in all the treated groups was comparable to the control up to and including the test concentration of 90.0 mg test item/kg soil dw. At the test concentration of 270 mg test item/kg soil dw and above, the feeding activity was reduced. Based on these findings, the 56-d EC10 for reproduction was determined to be 14.3 mg/kg soil dw.
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 14.3 mg/kg soil dw
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.