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EC number: 240-539-0 | CAS number: 16484-77-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Henry's Law constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- Henry's law constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The constant H of Henry's Law can be established experimentally for a specific compound or it can be determined from its vapor pressure and water solubility.
For a reliable calculation the miscibility of the substance with water should not exceed a few mole percent. If the water solubility is high or if the vapour pressure is very low, the result of the calculation is only valid for an orientation.
In the case of the test material both the vapour pressure and the water solubility are known. From these the Henry's Law Constant is calculated. - GLP compliance:
- not specified
- Key result
- H:
- 0 Pa m³/mol
- Temp.:
- 20 °C
- Remarks on result:
- other: Atmospheric pressure not specified
- Conclusions:
- Under the conditions of the study the Henry’s Law Constant for the test material was calculated to be 9.981 x 10^-8 (kPa m^3/mol).
- Executive summary:
The constant H of Henry's Law can be established experimentally for a specific compound or it can be determined from its vapour pressure and water solubility.
For a reliable calculation the miscibility of the substance with water should not exceed a few mole percent. If the water solubility is high or if the vapour pressure is very low, the result of the calculation is only valid for an orientation.
In the case of the test material both the vapour pressure and the water solubility are known. From these the Henry's Law Constant is calculated.
Under the conditions of the study the Henry’s Law Constant for the test material was calculated to be 9.981 x 10^-8 (kPa m^3/mol).
- Endpoint:
- Henry's law constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02 February 1999 to 22 June 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Henry’s Law constant for the test material was estimated from the vapour pressure and water solubility data in a guideline physico-chemical properties report.
- Principles of method if other than guideline:
- Henry’s Law constant for the test material was estimated from the vapour pressure and water solubility data in a guideline physico-chemical properties study report.
- GLP compliance:
- yes
- Key result
- H:
- 0 Pa m³/mol
- Temp.:
- 20 °C
- Conclusions:
- The volatility of the test material was estimated as Henry’s Law constant to be 1.7 x 10^-4 Pa.m3.mol-1.
- Executive summary:
Henry’s Law constant for the test material was estimated from the vapour pressure and water solubility data in a guideline physico-chemical properties report.
The volatility of the test material was estimated as Henry’s Law constant to be 1.7 x 10^-4 Pa.m3.mol-1.
Referenceopen allclose all
For the test material:
p = 4.0 x 10^-7 (kPa) at 20 °C
MW = 214.6 (g/mol)
c = 0.086 x 10^4 (g/m^3) at 20 °C
H = (4.0 x 10^-1 (kPa) ꞏ 214.6 g/mol) / (0.086 x10^4 g/m^3)
Henry’s Law Constant: H = 9.981 x 10^-8 (kPa m^3/mol)
H = P / s
At 20 °C, P = 7.1 x 10^-4 Pa
s = (0.8804 / 214.6) x 1000 mol m-3
H = (7.1 x 10^-4) / (0.8804 / 214.6) x 1000 mol m-3
Henry’s Law constant, H = 1.7 x 10 ^-4 Pa.m3.mol-1
The vapour pressure of the test material was found to be 1.4 x 10-3 Pa at 25°C. The volatility of the test material was estimated as Henry’s Law constant to be 1.7 x 10^-4 Pa.m3.mol-1.
Description of key information
Ohnsorge (1994)
Under the conditions of the study the Henry’s Law Constant for the test material was calculated to be 9.981 x 10^-8 (kPa m^3/mol).
Comb (2000b)
The volatility of the test material was estimated as Henry’s Law constant to be 1.7 x 10^-4 Pa.m3.mol-1.
The value from Comb (2000b) has been selected as the key value for chemical safety assessment in line with other EU regulatory schemes.
Key value for chemical safety assessment
- Henry's law constant (H) (in Pa m³/mol):
- 0
- at the temperature of:
- 20 °C
Additional information
Ohnsorge (1994)
The constant H of Henry's Law can be established experimentally for a specific compound or it can be determined from its vapour pressure and water solubility. The study was awarded a reliability score of 2 in accordance with the criteria set forth by Klimisch et al. (1997).
For a reliable calculation the miscibility of the substance with water should not exceed a few mole percent. If the water solubility is high or if the vapour pressure is very low, the result of the calculation is only valid for an orientation.
In the case of the test material both the vapour pressure and the water solubility are known. From these the Henry's Law Constant is calculated.
Under the conditions of the study the Henry’s Law Constant for the test material was calculated to be 9.981 x 10^-8 (kPa m^3/mol).
Comb (2000b)
Henry’s Law constant for the test material was estimated from the vapour pressure and water solubility data in a guideline physico-chemical properties report. The study was awarded a reliability score of 2 in accordance with the criteria set forth by Klimisch et al. (1997).
The volatility of the test material was estimated as Henry’s Law constant to be 1.7 x 10^-4 Pa.m3.mol-1.
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