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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The substance is not skin irritant and it is not eye irritant.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation/corrosion
The substance was tested for its skin irritation potential with an in vitro test according to OECD TG 439 Reconstructed human epidermis model. The mean cell viability of test item treated tissues was 73 % after 15 minutes exposure period and 42 hours of post-exposure incubation period. No classification for skin irritation of this substance is required according to the CLP Regulation (EC.n.1272/2008).
Eye irritation
The substance was tested for its eye irritation potential with an in vitro test according to OECD TG 492 Reconstructed human Cornea-like Epithelium (RhCE) test method. After 28 minutes exposure followed by product washing and a post incubation of 120 minutes a residual cell viability (mean of two replicates) of 87.5 % has been quantified for test item. No classification for eye irritation of this substance is required according to the CLP Regulation (EC.n.1272/2008).
Justification for classification or non-classification
According to the OECD TG 439 (EpiSkinTM/MTT Method) the test item is classified not irritant to skin if the mean relative viability is higher than 50 % according to the CLP Regulation (EC n.1272/2008). The substance "Reaction mass of dodecane-1-thiol and tridodecyl trithiophosphite" was tested for skin irritation according to OECD TG 439: the mean cell viability of the test item treated tissues was 73 % and therefore no classification for skin irritation/corrosion is required according to the CLP Regulation (EC n.1272/2008).
According to the OECD TG 492, the test item is classified not irritant to eyes if the mean relative viability is higher than 60 % according to the CLP Regulation (EC n.1272/2008). The substance "Reaction mass of dodecane-1-thiol and tridodecyl trithiophosphite" was tested for eye irritation according to OECD TG 492: the mean cell viability of the test item treated tissues was 87.5 % and therefore no classification is required for eye irritation according to the CLP Regulation (EC n.1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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