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EC number: 231-209-7 | CAS number: 7446-81-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- (Documentation of the older study falls short of today´s requirements, but corresponds to the standards at the time the study was conducted; the quality of the study performance is nevertheless not influenced. Sufficient data suitable for assessment.)
- Qualifier:
- according to guideline
- Guideline:
- ISO 8192 (Water quality - Test for inhibition of oxygen consumption by activated sludge for carbonaceous and ammonium oxidation)
- Deviations:
- no
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- - Laboratory culture: Municipal activated sludge from laboratory wastewater treatment plant fed with municipal sewage and synthetic wastewater.
- Initial biomass concentration: Concentration of dry substance = 1 g/L - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Nominal and measured concentrations:
- Nominal: control, 100, 500, 1000 mg/L
- Details on test conditions:
- - No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1 - Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
- Duration:
- 30 min
- Dose descriptor:
- other: EC20
- Effect conc.:
- 900 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Key result
- Duration:
- 30 min
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Results with reference substance (positive control):
- EC20 = 3 mg/L
EC50 = 10 mg/L
EC80 = ca. 150 mg/L
Reference
Description of key information
Based on results of the structural analogue acrylic acid (CAS# 79-10-7) the inhibition of degradation activity of activated sludge is not anticipated when sodium acrylate is introduced into biological treatment plants in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
No experimental data on the test substance is available. Sodium acrylate (NaA) is dissociating fast in aqueous media (Henderson – Hasselbach calculation). Therefore, the evaluation of the endpoint toxicity to microoranism is based on a weight of evidence approach using the data of the structural analogue acrylic acid (AA) (CAS 79-10-7) (for WoE information, see chapter 13.2).
In a test with domestic activated sludge the inhibition of oxygen consumption in the presence of AA was examined similar to guideline ISO 8192 (BASF, 1992). Since the study was performed before strict documentation processes were required, the documentation does not meet todays standards. Nevertheless, the quality of the study performance was not influenced. Therefore, the study was rated with the Klimisch score 2. After 30 minutes oxygen uptake was inhibited by 16 % at 500 mg/L and by 21 % at 1000 mg/L, the highest concentration tested. Thus, the EC20 was determined to be 900 mg/L.
A publication from Bringmann et al. give hints for a specific sensitivity of the protozoan Chilomonas paramaecium. In a 48-h cell multiplication inhibition test a Toxicity Threshold of 0.9 mg/L was determined. Although this species does not influence the degradation processes in a wastewater treatment plant itself, it is necessary for a proper function of a WWTP; therefore, the result of this study was used for derivation of the PNEC STP in the EU Risk Assessment.
In conclusion, based on the results of the structural analogue AA, inhibition of the degradation activity of activated sludge is not anticipated when NaA is introduced in appropriately low concentrations in WWTPs.
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