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EC number: 425-150-8 | CAS number: 94723-86-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study with analytical monitoring
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 425-150-8
- EC Name:
- -
- Cas Number:
- 94723-86-1
- Molecular formula:
- C15 H22 O3 S
- IUPAC Name:
- 2-butanoyl-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-one
- Details on test material:
- - Name of test material (as cited in study report): 625 Triketone
- Physical state: yellowish solid
- Analytical purity: 94%
- Batch No.: LJ 27881/1
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- mixture of sewage, soil and natural water
- Details on inoculum:
- - Source of inoculum/activated sludge: Activated sludge micro-organisms have been selected following recommendations in OECD guideline 301C. The sludge was prepared from 10 different sampling sites throughout federal state Rheinland-Pfalz, Germany:
- Domestic sewage plants of Bad-Dürkheim, Lambsheim and Weisenheim, Germany
- Industrial sewage plant of BASF
- River water samples of River Rhine near Altrip and of a river near Kleiniedesheim
- Lake water samples of lake "Große Blies" near Ludwigshafen, of lake "Silbersee" near Roxheim, of a pond near Bad-Dürkheim and of a pond near Labsheim
- Method of sampling: 1 L of activated sludge was taken from the aeration basins of each waste water treatment plant; 1 L of surface water and 1 L of aerobic soil of the banks were taken in the case of rivers and lakes
- Preparation of inoculum for exposure: Collected samples were thoroughly mixed and allowed to settle for 30 min. Floating matter was removed. About 1.7 L of the mixture were filtered. 1.5 L of the filtrate were mixed with 1.5 L filtered supernatant of the existing culture. The mixtrue was kept on a temperature range of 25 ± 2 °C and a pH range of 7.0 ± 1.0 °C.
- Concentration of sludge: 30 mg/L dry solids - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: Sapromat BOD Apparatus – respirometer with a manometric coulorimetric principle. In a closed system oxygen consuption was automatically re-added by an electrolytic oxygen generator. The produced oxygen is monitored in mg/L and these BOD values are continuously stored. Carbon dioxide produced was adsorbed using soda lime pellets. Agitation of the solution was brought about by rotary stirring
- Vessels: 500 ml glass bottles
- Preparation of test assays: Determination of the suspended solids level of the activated sludge culture was carried out using 50 ml of the activated sludge culture which were carried after filtration on a filter paper until constant weight. The suspended solids concentration of the prepared activated sludge suspension was 750 mg ss/L. 10 ml of this suspension was added to each test vessel with 240 ml test medium resulting in a suspended solids loading of 30 mg ss/L
- Light regime: The cultures were shielded from light
- Number of culture flasks/concentration: 3
SAMPLING
- Sampling frequency: daily
CONTROL AND BLANK SYSTEM
- Inoculum blank: 1
- Reference substance: 1
- Abiotic control: 1
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 25
- Sampling time:
- 28 d
- Details on results:
- Mean degradation kinetic [%]:
Day 7: 4
Day 14: 19
Day 21: 23
Day 28: 25
Day 28 residual test material analysis (mean): 93%
Specific chemical analysis
Blank test with water: 71.3 mg/L (residual amount of test substance at end of test)
Inoculated medium: < 0.5 mg/L (residual amount of test substance at end of test)
Primary degradation (inoculated medium): 93%
BOD5 / COD results
- Results with reference substance:
- Concentration of aniline at start of the test: 95 mg/L (residual amount of test substance at end of test)
Concentration of aniline at the end of the test: < 0.1 mg/L (residual amount of test substance at end of test)
Primary degradation: 99%
Applicant's summary and conclusion
- Interpretation of results:
- other: moderately biodegradable
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