Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
No information
Year:
1973
Bibliographic source:
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973

Materials and methods

Principles of method if other than guideline:
Guideline not known
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-aminophenol
EC Number:
204-616-2
EC Name:
4-aminophenol
Cas Number:
123-30-8
Molecular formula:
C6H7NO
IUPAC Name:
4-aminophenol

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
375 mg/kg bw
Based on:
not specified

Any other information on results incl. tables

Lungs, thorax or respiration: cyanosis

Behavioral: muscle weakness

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU