Registration Dossier
Registration Dossier
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EC number: 601-770-6 | CAS number: 121315-20-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- (2-{2-[(3-aminophenyl)formamido]ethanesulfonyl}ethoxy)sulfonic acid
- EC Number:
- 601-770-6
- Cas Number:
- 121315-20-6
- Molecular formula:
- C11H16N2O7S2
- IUPAC Name:
- (2-{2-[(3-aminophenyl)formamido]ethanesulfonyl}ethoxy)sulfonic acid
- Details on test material:
- FAT 92274/A
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Results and discussion
Any other information on results incl. tables
Under the experimental conditions employed substance induced erythema reactions when applied to the clipped albino rabbit skin.
The mean values of the recordings 24 to 72 hours after application are below the threshold of significance (2 score for erythema
or edema)
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- According to the EEC classification of the results obtained 24 to 72 hours after removing the bandages, the substance can be classified as
non-irritant in albino rabbits. The skin reactions observed were reversible until the end of the observation period on day 3. - Executive summary:
non-irritant in albino rabbits
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