N-nitro-N-(3-methyl-3,6-dihydro-2H-1,3,5-oxadiazin-4-yl)amine

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1996-07-03 until 1996-08-29

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline-conform study under GLP without deviations.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1996

Report date:

1996

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

yes

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

yes

Principles of method if other than guideline:

This study has been performed in accordance to the OECD Guidelines for Testing of Chemicals No. 104 and guideline 92/69/EEC, A.4. As mentioned in the OECD Guideline for Testing of Chemicals No. 104 p.2, 5, 6, several methods are applicable to the entire range of vapour pressures. However, in the lowest range the gas saturation method is recommended. In this laboratory, in this lowest vapour pressure range the thermobalance method instead of the gas saturation method is being used (developed in this laboratory, see B.F. Rordorf, A. Geoffroy. M. Szelagiewicz and E. Marti, "Vapour Pressure Methods for Industrial Applications" in Thermal Analysis. Proc. 6th lnt. Conf. Therm. Anal. Vol.1, ed. H.G. Wiedemann, Birkhauser. Basel, 1980, p.313). The validity of the thermobalance method was tested with benzoic acid. The agreement with literature was extremely good (e.g. OECD No.Guideline 104, p.4).

GLP compliance:

yes

Remarks:

Procedures are based on the OECD Principles of Good Laboratory Practice, 1981

Type of method:

other: thermo balance method

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

431-060-1

EC Name:

-

Cas Number:

153719-38-1

Molecular formula:

Hill formula: C4H8N4O3 CAS formula: C4H8N4O3

IUPAC Name:

3-methyl-N-nitro-3,6-dihydro-2H-1,3,5-oxadiazin-4-amine

Details on test material:

- Name of test material (as cited in study report): CA 2343
- Lot/batch No.: AMS 790/1
- Analytical purity: 99.7 %
- Storage: room temperature
- Reanalysis date: 06/99

Results and discussion

Vapour pressure

Vapour pressure 1

Temp.:

20 °C

Vapour pressure:

0 Pa

Remarks on result:

other: extrapolated

Vapour pressure 2

Temp.:

25 °C

Vapour pressure:

0 Pa

Remarks on result:

other: extrapolated

Transition / decomposition

Transition / decomposition:

yes

Transition temp.:

142.1 °C

Vapour pressure at 10°C above transition temperature:

21 Pa

Vapour pressure at 20°C above transition temperature:

310 Pa

Any other information on results incl. tables

Tab. 1 Vapour pressure curve

Temperature (°C)	Vapour pressure (Pa)
20	0.000015
25	0.000033
50	0.0011
100	0.33
142.1	13
150	21
200	310

Note:

- Vapour pressure at 150 °C is 21 Pa, instead of "vapour pressure at 10 °C above transition temperature = 21 Pa".

- Vapour pressure at 200 °C is 310 Pa, instead of "vapour pressure at 20 °C above transition temperature = 310 Pa".

Applicant's summary and conclusion

Conclusions:

- Vapour pressure at 20 °C: 0.00002 Pa (extrapolated)
- Vapour pressure at 25 °C: 0.00003 Pa (extrapolated)

Executive summary:

The purpose of this study was to determine the vapour pressure of test item CA 2343 (oxadiazinamine). This study has been performed in accordance to the OECD Guidelines for Testing of Chemicals No. 104 and guideline 92/69/EEC, A.4. However, instead of the gas saturation method, as recommnded by OECD Guideline 104, a thermobalance method developed by the performing laboratory was applied. The results of this method have been proven to agree extremely well with the results obtained by the OECD method.

The results for vapour pressure of CA 2343 are 0.00002 Pa (extrapolated) at 20 °C and 0.00003 Pa (extrapolated) at 25 °C. Thermal decomposition of the test item was observed at 142.1 °C.