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Diss Factsheets
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EC number: 300-344-4 | CAS number: 93925-42-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
see discussion
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.839 ng/L
Additional information
Read-across between dibutyltin compounds to to dibutyl diacetate concerning aquatic toxicity endpoints was considered appropriate as dibutyltin and octyltins are known to hydrolyse rapidly in water (as presented by Yoder 2003, under the data requirement hydrolysis), and form, in the case of dibutyltins, dibutyltin oxide.
The key study, Steger-Hartmann and Wendt (1998) has been allocated a Klimisch score of 2, as it was used as read across from a supporting substance. The study was performed to the guideline OECD 203. Only one fish died during the course of the 72 hour study, when tested up to the saturation point. Only a 72 hour LOEC of 3.1 mg/L could be determined from the study.
The Nagase et al (1991) study (the data were sourced from the same publication but reported as two separate endpoints, results from tests with dibutyltin di(acetate) and dibutyltin oxide respectively) have been allocated a Klimisch score of 4 due to a lack of detail in the reporting of the methods and results. Only 48 hours LC50's were reported. These studies are considered to be supporting studies.The 48 hr LC50 for di-n-butyltin diacetate was determined to be 1.07 x 10 -2 mmol dm-3 in the red killifish under semi-static conditions. For DBTO, the short term LC50 was 0.839 mg/L.
Tests in microorganism, algae and daphnia magna showed an different behavior and different effects in environment as the pure dibutyltin compound. In conculsion this endpoints are not applicable. In due to animal protection no new testing
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