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Diss Factsheets
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EC number: 809-434-2 | CAS number: 609783-45-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 Jan - 31 Jan 2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
- Report date:
- 2022
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- dynamic method
- Remarks:
- DSC
Test material
- Reference substance name:
- 4-Amino-2-fluoro-benzamide
- EC Number:
- 809-434-2
- Cas Number:
- 609783-45-1
- Molecular formula:
- C7H7FN2O
- IUPAC Name:
- 4-Amino-2-fluoro-benzamide
Constituent 1
Results and discussion
Boiling point
- Key result
- Decomposition:
- yes
- Decomp. temp.:
- 290 °C
- Remarks on result:
- other:
Any other information on results incl. tables
DSC-measurements
During the heating phase a distinct endothermic effect was observed in the temperature range of 130 – 160 °C, which can be assigned to the melting of the test item. As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 145.70 °C, this temperature can be used as melting point. The test item has a melting point of 145.7 °C. The test item showed a second endothermic signal in the temperature range of
290 – 380 °C, which could not be clearly assigned to the boiling of the test item. Thus, the photo cell detection method was performed. In the capillary, the first large bubble rises at 273 °C. At the same time, the test item changes colour from a clear, yellowish liquid to an orange, light brown liquid. It is concluded that the test item decomposes simultaneously with the start of boiling. Based on visual observation in the BÜCHI Apparatus it is stated that the test item has no boiling point but starts to decompose at a temperature of 290 °C. No further thermal effects were observed up to the test end temperature of 500 °C.
Results of DSC-measuremets
Measurement No. | Sample weight [mg] | Onset of Effect [°C] | Range of effect [°C] | Weight loss [mg] | Atmospheric pressure [hPa] |
1 | 8.70 | 145.70 318.56 | 130 - 160 (endo) 290 - 370 (endo) | 5.89
| 1022.3
|
2 | 9.57 | 145.69 321.88 | 130 - 160 (endo) 290 - 370 (endo) | 6.45 | 1023.4 |
Applicant's summary and conclusion
- Conclusions:
- The test item has no boiling point at atmospheric pressure (1022 - 1023 hPa) but starts to decompose at a temperature of 290 °C as determined by Differential Scanning Calorimetry and confirmed by the photo cell detection method.
- Executive summary:
Test Design: The determination of the boiling point of the test item was performed using Differential Scanning Calorimetry (DSC).
Result: The test item has no boiling point at atmospheric pressure (1022 - 1023 hPa) but starts to decompose at a temperature of 290 °C as determined by Differential Scanning Calorimetry and confirmed by the photo cell detection method.
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