Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

This transaminase is a white to coloured organic powder with a bulk density of 0.345 g/mL.  86.07% of the transaminase powder particles are distributed between 75 to 425 µm.  It is not possible to measure the full extent of water solubility as the solution becomes too viscous; therefore, the water solubility is reported as greater than 538 g/L. The measured partition coefficient n-octanol/water (log Pow) was determined to be -1.8.


 


A classical melting/boiling point assessment is not relevant for enzymes.  When heating enzymes above the biological conditions, typically 80 °C and higher, the attracting forces within the enzymes are broken, the fold is disrupted and the enzyme denatures. Denatured the enzymes lose their activity.


 


An enzyme in the solid phase will not transition to a liquid or vapor phase before the protein has first decomposed into smaller subunits, amino acids.  A vapour pressure of 1x10-6 Pa at 25 °C (EUSES min. default) will be used for the purposes of a Chemical Safety Assessment.  


 


Enzymes are proteins and have no surface tension activity when dissolved in water.  Also, enzymes are not self-igniting solids, nor are they flammable.  They do not have either explosive or oxidizing properties.

Additional information