Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 233-153-9 | CAS number: 10045-95-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 17 March 1997 - 21 March 1997
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- - a stock solution of approximately 1 % was prepared each day by dissolving the test substance directly into distilled water
- test solutions were prepared by adding proper amounts of stock solution and dilute further with dilution water to obtain the test concentrations
- for the preparation it was taken into account that the substance is an aqueous solution with approximately 55 % of neodymium nitrate - Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- - Common name: rainbow trout
- Strain: Walbaum
- Source: fish culture of Roger TEPPE, 01310 Polliat
- Age at study initiation (mean and range, SD): not reported
- Length at study initiation (length definition, mean, range and SD): 4.9 ± 0.7 cm
- Weight at study initiation (mean and range, SD): 1.3 ± 0.7 g
- Method of breeding: not reported
- Feeding during test: no
ACCLIMATION
- Acclimation period: 24 hours prior to start of test, selected fish were kept starved and placed in new aquaria
- Acclimation conditions (same as test or not): yes, same as test - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 110-140 ppm as CaCO3
- Test temperature:
- Definitive assay: 15.4 ± 1°C
Complementary assay: 15.3 ± 1°C - pH:
- Definitive assay: 7.4-8.0
Complementary assay: 7.8-8.2 - Dissolved oxygen:
- 70-78 %
- Salinity:
- Not applicable.
- Nominal and measured concentrations:
- Four assays were performed:
- Nominal concentrations during range-finding test: 1 and 10 mg/L
- Nominal concentrations during limit test: 100 mg/L
- Nominal concentrations during definitive test: 0.60, 1.4, 3.0, 6.7, 15 and 32 mg/L
- Nominal concentrations during complementary test: 0.1, 0.27 and 0.6 mg/L - Details on test conditions:
- TEST SYSTEM
- Test vessel: aquarium
- Material, size, headspace, fill volume: glass, 28 cm x 28 cm x 28 cm, headspace not reported, fill volume not reported
- Aeration: not reported
- Renewal rate of test solution (frequency/flow rate): after 24h, 48h and 72h living fish were transferred to fresh aquaria (with test solution or dilution water for the treatment and blanc fish respectively), while dead fish were removed
- No. of organisms per vessel: 5 for the four assays
- No. of vessels per concentration (replicates): 2 for the limit, definitive and complementary assays, 1 for the range-finding assay
- No. of vessels per control (replicates): 2 for the four assays
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: potable water, stabilised, dechlorinated by aeration
OTHER TEST CONDITIONS
- Adjustment of pH: not reported
- Photoperiod: 12:12 hours dark:light
- Light intensity: 1000 - 2000 lux at water surface
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): mortality after 3 hours and then daily
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 2.13 to 2.7 during the definitive and complementary assays
- Range finding study
- Mortality was observed at the three concentrations tested during the range-finder and limit test (1 mg/L: 0 % mortality, 10 mg/L: 80 %, 100 mg/L: 100 %). - Reference substance (positive control):
- yes
- Remarks:
- lindane
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: C.I.: 1.0-3.7 mg/L
- Details on results:
- - LC50(24h) = 23 mg/L, 95 % C.I. 15 - 50 mg/L
- LC50(48h) = 5.5 mg/L, 95 % C.I. 3.3 - 10 mg/L
- LC50(72h) = 2.1 mg/L, 95 % C.I. 1.1 - 4.1 mg/L - Results with reference substance (positive control):
- - LC50(24h) = 0.048 mg/L, 95 % C.I. 0.041 - 0.056 mg/L
- Reported statistics and error estimates:
- Probit analysis.
- Sublethal observations / clinical signs:
No analytical monitoring was performed to investigate the stability of the test item in the test media. Precipitation of Nd may have occurred; which could have led to an underestimation of the ecotoxicity. Therefore, the results should not be considered entirely reliable. However, as relatively important adverse effects were observed in this study underestimating toxicity, it may be used as supporting study.
- Validity criteria fulfilled:
- yes
- Conclusions:
- This study reported an LC50 of 2.0 mg Nd(NO3)3/L for Onchorhynchus mykiss after a 96-h exposure to neodymium nitrate. The results can not be considered entirely reliable as the test concentrations were not analytically verified and as precipitation may have occurred; which could have led to an underestimation of toxicity.
Reference
Description of key information
This study reported an LC50 of 2.0 mg Nd(NO3)3/L for Onchorhynchus mykiss after a 96-h exposure to neodymium nitrate. The results can not be considered entirely reliable as the test concentrations were not analytically verified and as precipitation may have occurred; which could have led to an underestimation of toxicity.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 2 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.