Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 860-352-3 | CAS number: 1610350-91-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2020-02-24 to 2020-04-27
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 Pa
- Temp.:
- 50 °C
- Vapour pressure:
- 0.006 Pa
- Conclusions:
- The vapour pressure of the test item was calculated to be 3.1E-4 Pa at 20, 5.3E-4 Pa at 25 and 5.8E-3 Pa at 50 °C, respectively.
- Executive summary:
A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item using the effusion method: vapour pressure balance. The thermal stability of the test item was determined with the DSC method. Starting at a temperature of 160 °C an exothermic effect with an energy release of -50 J/g can be observed. An endothermic effect observed starting at a temperature of 250 °C. Thus, the vapour pressure of the test item was determined at temperatures between 37 and 68 °C. Using the Antoine equation, the constants A and B were determined and the vapour pressure of the test item at 20, 25 and 50 °C was interpolated and extrapolated from the experimental vapour pressure. The vapour pressure was calculated to be 3.1E-4 Pa at 20, 5.3E-4 Pa at 25 and 5.8E-3 Pa at 50 °C, respectively.
Reference
Thermal Stability
Starting at a temperature of 160 °C an exothermic effect with an energy release of -50 J/g can be observed. An endothermic effect observed starting at a temperature of 250 °C.
Table 1: Results of the DSC-measurement
No. |
Sample weight / mg |
Start / °C |
Energy / J/g |
PN19280 |
7.00 |
160 |
-50 (exothermic) |
Effusion method: Vapour pressure balance
The vapour pressure was measured in the temperature range of 37 to 68 °C.
Table2: Results of the Effusion method
No. |
Temperature / °C |
Vapour pressure / Pa |
1 |
37 |
1.86E-3 |
2 |
42 |
2.76E-3 |
3 |
47 |
4.22E-3 |
4 |
52 |
6.79E-3 |
5 |
58 |
1.18E-2 |
6 |
63 |
1.75E-2 |
7 |
68 |
2.74E-2 |
From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation can be derived by regression of the data points to be:
A = 10.2276
B = -4027.25
C = 273.15.
The vapour pressure of the test item was calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50°C.
Table3: Calculated vapour pressure values for 20, 25 and 50 °C
Temperature / °C |
Vapour pressure / Pa |
20 |
3.1E-4 |
25 |
5.3E-4 |
50 |
5.8E-3 |
Description of key information
The vapour pressure of the test item was calculated to be 3.1E-4 Pa at 20, 5.3E-4 Pa at 25 and 5.8E-3 Pa at 50 °C, respectively (reference 4.6-1).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item using the effusion method: vapour pressure balance. The thermal stability of the test item was determined with the DSC method.Starting at a temperature of 160 °C an exothermic effect with an energy release of -50 J/g can be observed. An endothermic effect observed starting at a temperature of 250 °C.Thus, the vapour pressure of the test item was determined at temperatures between 37 and 68 °C. Using the Antoine equation, the constants A and B were determined and the vapour pressure of the test item at 20, 25 and 50 °C was interpolated and extrapolated from the experimental vapour pressure. The vapour pressure was calculated to be 3.1E-4 Pa at 20, 5.3E-4 Pa at 25 and 5.8E-3 Pa at 50 °C, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.