Registration Dossier
Registration Dossier
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EC number: 425-180-1 | CAS number: 66170-10-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.1; OECD 401 (1987)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 425-180-1
- EC Name:
- -
- Cas Number:
- 66170-10-3
- Molecular formula:
- C6H6Na3O9P
- IUPAC Name:
- trisodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-5-oxo-4-(phosphonatooxy)-2,5-dihydrofuran-3-olate
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- other: rat, Wistar CHBB:THOM (SPF)
- Strain:
- other: Wistar CHBB:THOM (SPF)
- Sex:
- male/female
Administration / exposure
- Vehicle:
- other: Aqua bidest.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- Male: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Symptoms of the male animals (cageside observations) and number of male animals showing symptoms: 5000 mg/kg bodyweight: Impaired general state H0 - H5 5 animals Poor general state H1 - H3 2 an
- Gross pathology:
- Effects on organs: Without finding
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
- Remarks:
- Migrated information. Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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