Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 253-379-1 | CAS number: 37172-53-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- Description: Clear colourless liquid
Test substance storage: At room temperature in the dark - Key result
- Water solubility:
- 186 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- 72 h
- Temp.:
- 20.1 °C
- pH:
- 6.7
- Details on results:
- - Preliminary test: The content of test substance dissolved in the water sample was 0.206 g/L. Value was obtained by extrapolation of the calibration curve.
- Main test: The maximum difference (MD) of the concentrations determined in the 24, 48 and 72 hour test samples was < 15%. According to the guidelines, the water solubility of the test substance is given as the mean value of the analysed concentrations. A small response at the retention time of the test substance (due to carry-over) was detected in the blank chromatogram. The maximum contribution of the response to the peak area of the test samples was 0.02%. According to this, the response was not considered to be significantly interfering to the analytical results of the test samples. The ratio of the response of the major component of the test substance and its isomer was similar in the test samples and calibration solutions. It demonstrated that the water solubility of the isomer is similar as the water solubility of the major component.
Reference
Water solubility of the test substance
Stirring time (h) |
Analysed conc. (g/L) |
Mean (g/L) |
MD (%) |
pH |
24 |
0.185 |
0.186 |
10 |
7.2 |
48 |
0.177 |
|
|
6.9 |
72 |
0.196 |
|
|
6.7 |
Description of key information
The water solubility of the test substance is 186 mg/L
Key value for chemical safety assessment
- Water solubility:
- 186 mg/L
- at the temperature of:
- 20.1 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
