3β-hydroxyandrost-5-en-17-one acetate

Auto flammability

Link to relevant study record(s)

Reference

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 May 2017 - 16 June 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

- Batch n°: M16GB2547
- Purity: 99.6 % (w/w) (based on assay of T008506)
- Test item storage: At room temperature
- Stable under storage conditions until: 01 July 2018 (retest date)

Key result

Remarks on result:

no self-ignition observed up to the melting point

No spontaneous ignition occurred and no exothermic effect was observed. It demonstrated that the test item is "not a self-heating substance". According to the UN guideline, no further testing is required.

After the experiment, the test item had turned into an orange residue and was collected in a container that was placed below the cube. It indicated that the test item had melted, decomposed and/or reacted during the experiment.

 

Conclusions:

Based on the results of the EC A.16 test performed, the test item is considered ‘not self-ignitable’.

Because there were no indications of self-heating observed in this test, the test item was considered ‘not self-heating’ and the main study according to UN N.4 was not performed.

Description of key information

The auto-flammability potential of T008506 was determined in a K1 GLP study (Ciric, 2017) carried out according to EC A.16. In the EC A.16 test no self-heating was observed up to the melting point of the test item. No relative self-ignition temperature could be determined.