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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Patty’s Toxicology
Author:
Bingham E. and Cohrssen B. (Eds.)
Year:
2012
Bibliographic source:
6 Volume Set, 6th Edition. John Wiley & Sons: New York

Materials and methods

GLP compliance:
not specified
Test type:
other: not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Lauric acid
EC Number:
205-582-1
EC Name:
Lauric acid
Cas Number:
143-07-7
Molecular formula:
C12H24O2
IUPAC Name:
Dodecanoic acid

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
12 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Lauric acid (metabolite of sodium lauroyl lactylate) has a reported acute oral LD50 of 12,000 mg/kg in rats.
Executive summary:

According to the 6th edition of the Patty's Toxicology handbook, lauric acid (metabolite of sodium lauroyl lactylate) has a reported acute oral LD50 of 12,000 mg/kg in rats.