2-ethoxy-4-(hydroxymethyl)phenol

Density

Administrative data

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental starting date: 31 July 2016 Experimental completion date: 12 October 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

GLP compliance:

yes

Type of method:

pycnometer method

Test material

Test material information

Constituent 1

Reference substance name:

2-ethoxy-4-(hydroxymethyl)phenol

EC Number:

674-192-5

Cas Number:

4912-58-7

Molecular formula:

C9H12O3

IUPAC Name:

2-ethoxy-4-(hydroxymethyl)phenol

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

Information as provided by the Sponsor. The Certificate of Analysis provided by the Sponsor is presented as.

Identification: EVA
Common name: ETHYLVANILLYL ALCOHOL, White Vanilla
CAS Number: 4912-58-7
CAS Name: Benzenemethanol, 3-ethoxy-4-hydroxy-
Chemical Name: 2- Ethoxy-4-(hydroxymethyl)phenol
Appearance/Physical state: Pale yellow powder
Batch: 4K0001
Purity: 100%
Expiry date: 31 December 2017
Storage conditions: Room temperature in the dark

Results and discussion

Density

Key result

Type:

relative density

Density:

ca. 1.31 other:

Temp.:

20 °C

Any other information on results incl. tables

Calibration

The pressure readings and the calculated volume for the reference and sample cells are shown in the following table:

Determination	P1(psig)	P2(psig)	P3(psig)	P4(psig)	Reference Cell volume (cm^3)	Sample Cell Volume (cm^3)
1	17.287	6.549	17.256	8.553	90.916	149.069
2	17.347	6.572	17.288	8.568	90.961	149.134
3	17.226	6.528	17.236	8.541	91.113	149.314

Mean reference cell volume : 90.997 cm³ Mean sample cell volume : 149.173 cm³

As the reference cell volume and sample cell volume were within the defined tolerance (90.953 ± 1.0 cm³ and 149.225 ± 1.0 cm³ for the reference and sample cell volumes respectively) the gas comparison pycnometer was therefore considered acceptable for use.

Sample

The pressure readings, calculated volumes and density values obtained for the test item are shown in the following table:

Determination	Test	P1(sample)(psig)	P2(sample)(psig)	Volume (cm^3)	Density (kg/m^3)	Mean Density (kg/m^3)
1	A	17.265	7.465	29.713	1.310 x 10^3	1.308 x 10^3
	B	17.292	7.479	29.778	1.307 x 10^3
	C	17.299	7.481	29.749	1.308 x 10^3
2	A	17.223	7.443	29.604	1.310 x 10^3	1.309 x 10^3
	B	17.284	7.469	29.594	1.310 x 10^3
	C	17.264	7.464	29.697	1.306 x 10^3

Mean density : 1.31 x 103 kg/m³

Relative density : 1.31

Temperature : 20.0 ± 0.5 °C

Discussion

Duplicate determinations were performed to ensure a reproducibility of less than ± 20 kg/m³ was obtained.

Applicant's summary and conclusion

Conclusions:

The density of the test item has been determined to be 1.31 kg/m3 at 20.0 ± 0.5 °C; relative density: 1.31.

Executive summary:

The determination was carried out using a gas comparison pycnometer and a procedure designed to be compatible with Method A.3 Relative Density of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 109 of the OECD Guidelines for Testing of Chemicals, 02 October 2012.

Conclusion

The density of the test item has been determined to be 1.31 kg/m3 at 20.0 ± 0.5 °C; relative density: 1.31.