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EC number: 210-784-8 | CAS number: 623-27-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187 “Particle Size Analysis by Laser Diffraction”, Handbook K, 2007
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- Terephthalaldehyde
- EC Number:
- 210-784-8
- EC Name:
- Terephthalaldehyde
- Cas Number:
- 623-27-8
- Molecular formula:
- C8H6O2
- IUPAC Name:
- benzene-1,4-dicarbaldehyde
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- Batch (Lot) Number: 180401
Expiry date: 01 April 2020 (retest date)
Physical Description: Light yellow powder
Purity/Composition: 99.6%
Storage Conditions: At room temperature
Results and discussion
- Mass median aerodynamic diameter:
- ca. 57.2 µm
- Geometric standard deviation:
- ca. 2.348
Particle sizeopen allclose all
- Percentile:
- D10
- Mean:
- ca. 14.6 µm
- St. dev.:
- 0.036
- Percentile:
- D50
- Mean:
- ca. 49.1 µm
- St. dev.:
- 0.377
- Percentile:
- D90
- Mean:
- ca. 129 µm
- St. dev.:
- 0.753
Any other information on results incl. tables
During the method development phase of the analysis trials were conducted using the dry
powder module (DPM) only. The results of these trials indicated that the most appropriate
test and material parameters to obtain the optimum measurements were:
Module : DPM
Dispersant : Air
Dispersion pressure : 0.5 barg
Refractive index (sample) : 1.500 n
Absorption : 0.000 AU
Analysis Model : General Purpose
Using the identified parameters, the particle size was analysed over the range 0.01 µm to
3500 µm. The results of the formal analysis are presented in Table 9:1. In addition, a graph
of volume (%) versus Particle Diameter (µm), and full particle size distribution, is provided in
Graph 9.A (Average of 5 runs).
Table 9:1 : Full Test Results
run 1 | run 2 | run 3 | run 4 | run 5 | average | STDVP | %STDVP | |
VWM | 62.6 | 62.4 | 63.0 | 62.8 | 62.8 | 62.7 | N/A | N/A |
MODE | 55.0 | 54.9 | 56.0 | 56.1 | 56.0 | 55.6 | N/A | N/A |
D10 | 14.6 | 14.7 | 14.7 | 14.6 | 14.7 | 14.6 | 0.0364 | 0.248 |
D50 (MEDIAN) | 48.7 | 48.7 | 49.3 | 49.3 | 49.4 | 49.1 | 0.377 | 0.767 |
D90 | 128 | 128 | 129 | 129 | 129 | 129 | 0.753 | 0.585 |
MMAD | 56.7 | 56.8 | 57.5 | 57.5 | 57.6 | 57.2 | 0.393 | 0.7 |
GSD | 2.350 | 2.345 | 2.351 | 2.348 | 2.345 | 2.348 | 0.002 | 0.1 |
All particle size results are in µm
5.27 % by volume of sample was seen to be < 10.00 µm
Definitions
VWM : volume weighted mean
d10 : 10 % of the test item is less than this particle size
d50 : 50 % of the test item is less than this particle size
d90 : 90 % of the test item is less than this particle size
GSD : geometric standard deviation of the lognormal particle size distribution
MMAD : mass median aerodynamic diameter
Average : calculated from the entirety of the data captured in each run and not a
simple arithmetic mean
STDVP : standard deviation of the population
% STDVP : percentage standard deviation of the population
The coefficient of variation for d50 is less than 3 %; d10 and d90 are less than 5 %. Thus
repeatability of the characteristic particles in the size distribution is within the acceptable
limits as per the ISO 13320-1 test standard.
Applicant's summary and conclusion
- Conclusions:
- The MMAD of the tested sample was measured as 57.2 µm, with a volume weighted mean of 62.7 µm. The particle distribution was as follows: d10 14.6µm, d50 49.1µm and d90 129µm. The volume of sample<10µm was 5.27%.
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