Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Toxic effect type:
dose-dependent

Effects on fertility

Description of key information

The substance is only manufactured and used under strictly controlled conditions during its whole lifecycle and thus this endpoint does not need to be further investigated. For further details please refer to the report “Exposure based adaptation information - N1,N3-diallylpropane-1,3-diamine dihydrochloride” attached in IUCLID Chapter 13.

Link to relevant study records

Referenceopen allclose all

Endpoint:
screening for reproductive / developmental toxicity
Data waiving:
exposure considerations
Justification for data waiving:
the study does not need to be conducted because relevant human exposure can be excluded as demonstrated in the relevant exposure assessment
Endpoint:
extended one-generation reproductive toxicity - basic test design (Cohorts 1A, and 1B without extension)
Data waiving:
exposure considerations
Justification for data waiving:
the study does not need to be conducted because relevant human exposure can be excluded as demonstrated in the relevant exposure assessment
Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available

Effects on developmental toxicity

Description of key information

The substance is only manufactured and used under strictly controlled conditions during its whole lifecycle and thus this endpoint does not need to be further investigated. For further details please refer to the report “Exposure based adaptation information - N1,N3-diallylpropane-1,3-diamine dihydrochloride” attached in IUCLID Chapter 13.

Link to relevant study records
Reference
Endpoint:
developmental toxicity
Data waiving:
exposure considerations
Justification for data waiving:
the study does not need to be conducted because relevant human exposure can be excluded as demonstrated in the relevant exposure assessment
Species:
rat
Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

The substance is only manufactured and used under strictly controlled conditions during its whole lifecycle and thus this endpoint does not need to be further investigated. For further details please refer to the report “Exposure based adaptation information - N1,N3-diallylpropane-1,3-diamine dihydrochloride” attached in IUCLID Chapter 13. Based on the exposure assessment, classification of the substance is therefore not warranted.

Additional information