Iodo(triphenylphosphino)copper

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

2003

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Considering the structural similarities of the substances "Iodo(triphenylphosphino)copper" and "Iodotris(triphenylphosphino)copper" and the almost identical physical and chemical properties, especially partition coefficients and water solubilites, it can be expected that these substances will show quite similar behaviour with respect to their biodegradability behaviour, too.

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

other: OECD 301B (Mod. Sturm)

GLP compliance:

yes

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 219001
- Expiration date of the lot/batch: Sept. 23rd 2003

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in a closed polyethylene vessel at room temperature.
- Stability under test conditions: in solution at room temperature stable for at least 96 hours

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge (adaptation not specified)

Details on inoculum:

Activated sludge from a biologic sewage treatment plant was used. The chosen plant is
treating mostly household sewage.

Duration of test (contact time):

28 d

Parameter followed for biodegradation estimation:

CO2 evolution

Reference substance:

other: Anilin

Preliminary study:

Before the start of the test, the toxicity of the test item towards activated sludge was determined in a separate study (respiration inhibition test).
The test item didn't have a toxic effect on the activated sludge. The carbon content of 66 % was determined from the formula. The test item was directly weighed into the test flasks.

Parameter:

other: degradation

Value:

12

Sampling time:

28 d

Details on results:

Points of degradation plot (test substance):
0 % degradation after 2 d
3 % degradation after 4 d
6 % degradation after 8 d
6 % degradation after 15 d
9 % degradation after 21 d
12 % degradation after 28 d

Results with reference substance:

Points of degradation plot (reference substance):
0 % degradation after 2 d
1 % degradation after 4 d
60 % degradation after 8 d
81 % degradation after 15 d
81 % degradation after 21 d
97 % degradation after 28 d

The 10 d-window began on day 24, therefore the criteria of the pass level of 60% within 10 days given in the OECD guideline couldn 't be determined.

The degree of biodegradation reached 12 % after 28 days.

The test item is considered as „not readily biodegradable".

Day	Ref.1	Ref.2	Test 1	Test 2	Mean	abiot.	Toxiz.
2	-0,3	-0,1	2	2,7	2,4	3,9	0,7
4	0,7	0,5	2,8	3,8	3,3	4,6	8,2
6	47,4	47	4,6	5,5	5	5,6	28,2
8	60,2	62,5	5,9	6,1	6	5,4	37,5
11	73,8	71,1	7,4	6,9	7,2	6,2	43,8
15	81,3	76,5	6,2	7	6,6	7,7	44,9
21	84,5	80,9	8,8	7,8	8,3	9,6	45,8
28	96,7	90,4	12,2	11,8	12	13,3	48,9

Validity criteria fulfilled:

yes

Interpretation of results:

other: not readily biodegradable

Conclusions:

The test item is considered as „not readily biodegradable".

Executive summary:

The test item is considered as „not readily biodegradable".

Description of key information

Not readily biodegradable, shown on a structural analogue.

Key value for chemical safety assessment

Biodegradation in water:

under test conditions no biodegradation observed

Additional information

Results on the structural similar compound Iodotris(triphenylphosphino)copper suggest a low biodegradability for Iodo(triphenylphosphino)copper, too.