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EC number: 219-354-4 | CAS number: 2424-01-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01Mar2018 to 13Mar2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Lot 20160912
- Purity: 99.2%
- Expiration date of the lot/batch: 1-August-2018
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: at room temperature
- Stability under test conditions: test substance stable - Key result
- Boiling pt.:
- 112.3 °C
- Atm. press.:
- 1 006 hPa
- Decomposition:
- no
- Conclusions:
- The boiling point of MTDID 49220 was determined as 112.3 °C at 1006 hPa, as determined by EU Method A.2.
- Executive summary:
The boiling point of MTDID 49220 was tested using differential scanning calorimetry (DSC) in three experiments. The boiling point was determined as 112.3 °C at 1006 hPa. The boiling temperature was determined as the mean evaporation temperature of two trials done under comparable conditions. The study was conducted in accordance with EU Method A.2 and was GLP compliant; therefore the study is considered reliable without restrictions.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Qualifier:
- no guideline available
- Version / remarks:
- Summary of various published results. Details of methods were not obtained.
- Principles of method if other than guideline:
- Summary of various published results, assumed to have been obtained with various methods.
- GLP compliance:
- not specified
- Boiling pt.:
- >= 108 - <= 113 °C
- Remarks on result:
- other:
- Remarks:
- Summary of various published results.
- Conclusions:
- MTDID 49220 has published boiling points which range from 108 °C to 113 °C.
- Executive summary:
A search of the Reaxys chemistry database (Elsevier Publishing) found published boiling points ranging from 108 °C to 113 °C for MTDID 49220. The atmospheric pressure was included for only a few results, but the boiling points are presumed to have been measured at, or near standard atmospheric pressure. The results are considered supporting information, as methodoligical information was not obtained, and their reliability is not assignable.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM D1120-94 “Standard Test Method for Boiling Point of Engine Coolants."
- GLP compliance:
- not specified
- Type of method:
- dynamic method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Lot 20160912
- Purity: 99.2%
- Expiration date of the lot/batch: 1-August-2018
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Stability under test conditions: test substance stable at room temperature - Key result
- Boiling pt.:
- 112.3 °C
- Atm. press.:
- 1 013.25 hPa
- Conclusions:
- The boiling point of MTDID 49220 was found to be 112.3 °C at 1013.25 hPa, according to ASTM D 1120-94.
- Executive summary:
The boiling point of MTDID 49220 was tested using the dynamic method according to ASTM D 1120 -94. The boiling point was determined as 112.3 °C at 1013.25 hPa. The study was conducted in accordance with a national standard method, and therefore it is considered reliable without restrictions.
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no information regarding method available
- Key result
- Boiling pt.:
- 111 °C
- Atm. press.:
- 1 013.25 hPa
- Conclusions:
- A boiling point of 111 °C at 1013.25 hPa was reported for MTDID 49220 on a Safety Data Sheet.
- Executive summary:
A boiling point of 111 °C at 1013.25 hPa was reported for MTDID 49220 on a Safety Data Sheet. No information was available regarding the method used to measure the boiling point and therefore the reliability of this result is not assignable.
Referenceopen allclose all
The DSC-curve obtained with Experiment 1 is shown in Figure 1. An endothermic peak between 50 °C and 150 °C was observed. The extrapolated onset temperature of the peak was 112.588 °C. The endothermic effect was most likely obtained due to boiling of the test substance. After the experiment it was observed that the test substance had evaporated from the sample container. A light brown deposit remained in the sample container.
A higher heating rate of 50 °C/minute was applied in Experiment 2 (see Figure 2) to investigate the endothermic peak. The extrapolated onset temperature of the endothermic peak in Experiment 2 was 111.673 °C. The endothermic peak had not shifted to higher temperatures. It demonstrated that boiling of the test item caused the endothermic effect. After the experiment, it was observed that the test item had evaporated from the sample container. A light brown deposit remained in the sample container. Since a higher heating rate was applied, the extrapolated onset temperature of the boiling peak was not used for calculation of the boiling temperature.
Experiment 3 was performed as a duplicate of Experiment 1, but without the cooling cycle (see Figure 3). Similar results as in Experiment 1 were obtained. The extrapolated onset of the boiling peak was 112.019 °C. After the experiment, it was observed that the test item might have been evaporated from the sample container. After the experiment, it was observed that the test item had evaporated from the sample container. A light brown deposit remained in the sample container.
The boiling temperature was determined as the mean boiling temperature of Experiment 1 (112.588 °C) and Experiment 3 (112.019 °C).
Elsevier Reaxys Database Search Results for Boiling Point of MTDID 49220
Boiling Point [°C] | Pressure (Boiling Point) [Torr] | References |
108 - 110 | Vasilieva; Kleshcheva; Gromova; Rebrov; Filatova; Krut'ko; Timofeeva; Topchiev; Russian Chemical Bulletin; vol. 49; nb. 3; (2000); p. 431 - 437 | |
109 - 111 | 721 | Voronkov, M.G.; Kirpichenko, S.V.; Abrosimova, A.T.; Keiko, V.V.; Albanov, A.I.; J. Gen. Chem. USSR (Engl. Transl.); vol. 61; nb. 9.2; (1991); p. 2033 - 2039,1883 - 1888 |
111 - 113 | Barluenga, J.; Najera, C.; Yus, M.; Journal of Heterocyclic Chemistry; vol. 17; (1980); p. 917 - 921 | |
111 - 112 | 760 | Duschek,C. et al.; Journal fuer Praktische Chemie (Leipzig); vol. 317; (1975); p. 491 - 502 |
112 - 113 | Tabushi et al.; Nippon Kagaku Zasshi; vol. 90; (1969); p. 197,198,201 | |
112 | Partheil; von Broich; Chemische Berichte; vol. 30; (1897); p. 618; van Overbeke; Glacet; Bulletin de la Societe Chimique de France; (1962); p. 936; Dieck; Friedel; Journal of Organometallic Chemistry; vol. 12; (1968); p. 173,176, 178, 179 | |
108 - 112 | 760 | Hennion,G.F.; Ode,R.H.; Journal of Organic Chemistry; vol. 31; (1966); p. 1975 - 1977 |
Description of key information
The boiling point of MTDID 49220 was determined as 112.3 °C at 1006 hPa. The study was conducted in accordance with EU Method A.2 and was GLP compliant; therefore the study is considered reliable without restrictions.
Key value for chemical safety assessment
Additional information
In a supporting study, the boiling point of MTDID 49220 was tested using the dynamic method according to ASTM D 1120 -94, and determined as 112.3 °C at 1013.25 hPa. The study was conducted in accordance with a national standard method, and therefore it is considered reliable without restrictions. Boiling point values were found in two additional sources, but the reliability of these could not be determined, and they are not further considered.
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