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Diss Factsheets
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EC number: 700-217-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Plant drainage testing method, acute toxicity test of fish and shellfish (71. of JIS K 0102-1998).
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 210 (Fish, Early-Life Stage Toxicity Test)
- GLP compliance:
- yes
Test material
- Details on test material:
- - Purity: 100% as a reaction product
Constituent 1
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
Dispersant: HCO-40
The provided samples and HCO-40 at 20 times its amount were dissolved in acetone, and after distilling the acetone, ion-exchange water was added, so that a stock solution with a test substance concentration of 1000 mg/L was prepared. The operation was carried out under a light-shielded condition.
Test organisms
- Test organisms (species):
- Oryzias latipes
- Details on test organisms:
- Kind of fish: Rice fish, Medaka, Oryzias latipes
Reason for selection: Since the sensitivity is similar to that of carp and it is easily obtained as a fish for testing.
Supply source: Ogawa Shoten
Cumulative culture condition: Upon receipt, abnormal fish were removed, and the remaining fish were treated with a medication in a cumulative culture tank and held for 12 days in a flow-water state.
Domestication condition: After the cumulative culture, the fish were transferred to a domestication tank, treated with a medication, and domesticated. During the domestication, abnormal fish were removed, and the remaining fish were held for 15 days in a flow-water state at a water temperature of 25 ± 2ºC. Then, the fish were sorted, treated with a drug, and held for 38 days under flow-through conditions.
Weight: Average 0.22 g
Total length: Average 3.0 cm
Sensitivity test: The 48-h LC50 value of a reference material PCP-Na (pentachlorophenol sodium reagent using the test fish of the same lot was 0.420 mg/L.
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 24.1ºC
- pH:
- 7.9
- Dissolved oxygen:
- At time of exposure start 7.9 mg/L
Before water exchange 6.5 mg/L - Nominal and measured concentrations:
- 250 mg/L
- Details on test conditions:
- Number of provided fish: 10 fish/concentration level
Exposure period: 96 h
Exposure method: Half water cut-off type (water exchange every 8-16 h) m-- static renewal
Illumination: Under a light-shielded condition for the exposure period. - Reference substance (positive control):
- yes
- Remarks:
- Pentachlorophenol sodium reagent
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 250 mg/L
- Details on results:
- 96-h LC50 value of the test substance > 250 mg/L
96-h LC50 value was calculated by the Doudoroff method.
The concentration of the dispersant (HCO-40) used at that time was 5000 mg/L and the 96-h LC50 value of the dispersant was 50000 mg/L, the test at a concentration higher than that was not carried out in consideration of the influence of the toxicity of the dispersant.
Applicant's summary and conclusion
- Conclusions:
- 96-h LC50 was > 250 mg/L
- Executive summary:
This OECD 210 study with Oryzias latipes was part of a BCF study with Carp. The 96-h LC50 was determined to be > 250 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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