Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-116-8 | CAS number: 4203-89-8
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- estimated by calculation
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- substance is rapidly hydrolyzed
Data source
Reference
- Reference Type:
- other: calculation
- Title:
- No information
- Author:
- Advanced Chemistry Development
- Year:
- 2 011
- Bibliographic source:
- Advanced Chemistry Development Software V11.02
Materials and methods
- Principles of method if other than guideline:
- calculation
Test material
- Reference substance name:
- 2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate
- EC Number:
- 224-116-8
- EC Name:
- 2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate
- Cas Number:
- 4203-89-8
- Molecular formula:
- C14H23NO3
- IUPAC Name:
- 2-{1-oxa-4-azaspiro[4.5]decan-4-yl}ethyl 2-methylprop-2-enoate
- Test material form:
- liquid
Constituent 1
Results and discussion
Bioaccumulation factor
- Temp.:
- 25 °C
- Type:
- other: log BCF
- Value:
- 1.72 dimensionless
- Remarks on result:
- other: calc for pH 1-10
- Remarks:
- Note: substance is rapidly hydrolyzed
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Remarks:
- calculation
- Conclusions:
- Calculation is an estimate - model does not take hydrolysis into account, the substance rapidly hydrolyzes. Calculated log BCF = 1.72 for pH 1-10 @ 25 oC
- Executive summary:
Calculation is an estimate - model does not take hydrolysis into account, the substance rapidly hydrolyzes. Calculated log BCF = 1.72 for pH 1-10 @ 25 oC
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
