Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 279-013-0 | CAS number: 78948-87-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1982
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study without analytical monitoring, but study is well documented. This is only a minor shortcoming and do not affect the overall significance of the findings.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- adopted April 1981
- Deviations:
- yes
- Remarks:
- Test duration extended to 48 hours (which was optional, according to OECD guideline 202 adopted April 1981). However, this duration is usual today.
- GLP compliance:
- no
- Remarks:
- GLP was not compulsory at the time the study was performed (1982). Experimental procedures and study report were reviewed by the laboratory’s quality assurance unit
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Name of test material in study report: Magnesium-monoperoxyphthalate-hexahydrate, H48
OTHER SPECIFICS:
white powder - Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna STRAUS
- Strain/clone: no data
- Age of parental stock: < 24 h at test initiation
- Feeding during test: no
ACCLIMATION
- Type and amount of food: Suspension of trout chow and alfalfa (PR-11) supplemented with algae (Selenastrum capricornutum), amount not stated
- Feeding frequency: At least every three days prior to testing - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 255 mg/L as CaCO3
- Test temperature:
- 20 °C +- 2.0 °C
- pH:
- 7.8 – 8.6
- Dissolved oxygen:
- 7.5 - 8.6 mg/L
- Conductivity:
- 50 µmhos/cm
- Nominal and measured concentrations:
- Initial concentrations: control, 10, 18, 32, 56 and 100 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 250 mL beakers, containing 200 mL medium (well water)
- Aeration: no
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Well water at ABC's Aquatic Bioassay Laboratory
- Alkalinity: 368 mg/L as CaCO3
- Culture medium different from test medium: no
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8 hours light:dark
- Light intensity: 50 - 70 footcandles (One footcandle is approximately 10.76 lux).
EFFECT PARAMETERS MEASURED:
Immobility, sampled after 24 and 48 hours - Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 32 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 42 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 56 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Reported statistics and error estimates:
- Calculation of the median effective concentration causing 50% effect (EC50) by binominal test
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test results indicate that MMPP is acutely harmful towards Daphnia.
- Executive summary:
The acute toxicity of MMPP towards invertebrates was performed according to the OECD guideline 202 (1981). The water flea Daphnia magna STRAUS (Crustacea: Cladocera) was used.
Animals were exposed to several of H48 concentrations, ranging from 10 to 100 mg/L. The test was performed at 20.0°C and a 16:8 light:dark cycle in well water. Immobilisation was assessed at 24 and 48 hours, physico-chemical water parameters were measured at 0 and 48 hours.
Analytical monitoring of test concentration was not performed. Volatility and adsorption of MMPP from aqueous solutions can be neglected and therefore these properties have no influence on the result. However, MMPP hydrolyses in aqueous solution and MMPP is regarded as readily biodegradable; both effects may reduce the nominal concentration. Nevertheless, an analytical monitoring is not necessary, as the aqueous solution of MMPP reflects the emission of hydrolyses products to aquatic organisms. Furthermore, the biodegradability is assumed to have only minor effects on the results due to the relatively short test duration. The concentration in aqueous solution is assumed to be sufficiently stable under the test conditions due to the analytical results shown in the algae growth inhibition test.All other validity criteria according the test guidline OECD 202 are met within the study
Reference
Effect data (Immobilisation)
|
Results
|
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 42 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.