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Diss Factsheets
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EC number: 947-782-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- January 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test)
- Version / remarks:
- 2014
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Liquid sewage (aerobic sludge), treatment plant of urban (about 66%) and industrial (about 34%)
- Details on inoculum:
- - Source of inoculum/activated sludge: BRIANZACQUE SRL (Monza), San Rocco - Monza (MB), Italia. Sludge was mixed in the laboratory and left to settle in aerobic conditions.
- Pre-treatment: Prior to use the sludge was analysed to determine its ability to form colony units. The sludge was later centrifuged, washed, and analysed to quantify the suspended solid concentration. The inoculum was prepared to have a suspended solid concentration of 4 mg/L. - Duration of test (contact time):
- 56 d
- Initial conc.:
- 18.81 mg/L
- Based on:
- TOC
- Parameter followed for biodegradation estimation:
- other: TIC (Total Inorganic Carbon)
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Solution A: KH2PO4 (8.50 g/l); K2HPO4 (21.75 g/l); Na2HPO4. 2H2O (33.40 g/l), NH4 CI (0.50 g/l). Solution B: CaCl2 2H2O (36.40 g/l). Solution C: MgSO4 7H2O (22.50 g/l). Solution D: FeCl3.6 H2O (0.25 g/l). All solutions have been made with deionised water (MilliQ Millipore).
- Test temperature: 20 °C.
- Suspended solids concentration: 4 mg/L.
- Continuous darkness: Yes.
- Other: 12-hours before determining TIC, 6 ml sodium hydroxide (1 M) was added to one bottle each of the blank, reference substance, and test item in order to stop further reaction.
TEST SYSTEM
- Culturing apparatus: Glass bottles with hermetic seal (GHIARONI)
- Number of culture flasks/concentration: There were 29 bottles each prepared the blank, test sample, and reference substance (87 in total; 3 replicates for sampling once per week, and 5 on day 28). 11 bottles were prepared for the test sample + reference substance (3 replicates for day 1 and 56, and 5 on day 28).
- Method used to create aerobic conditions: During the experimental set-up, sludge was mixed, permitted to settle, and then kept in aerobic conditions.
- Measuring equipment: Shimadzu Carbon Analyzer (SHIMADZU); Multiparametric (pH, O2, temperature) (WTW); Infrared Gas Analyzer (NDIR).
- Test performed in open system: Glass bottles were sealed as part of a headspace test.
SAMPLING
- Sampling frequency: Days 0, 1, 7, 14, 21, 28, 35, 42, 49, and 56.
CONTROL AND BLANK SYSTEM
- Inoculum blank: Untreated inoculum.
- Toxicity control: Test substance + reference substance. - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- Initial concentration: 19.05 mg/L TOC
- Test performance:
- The quality criteria of the test were satisfied. TIC in the blank control on day 56 was <3 mg C/L. The test sample + reference substance treatment confirmed a lack of an inhibitory effect of the test sample on the inoculum.
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 0
- Sampling time:
- 0 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 4
- Sampling time:
- 1 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 10
- Sampling time:
- 7 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 6
- Sampling time:
- 14 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 15
- Sampling time:
- 21 d
- Key result
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 17
- Sampling time:
- 28 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 6
- Sampling time:
- 35 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 3
- Sampling time:
- 42 d
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 11
- Sampling time:
- 49 d
- Key result
- Parameter:
- other: % degradation (TIC removal)
- Value:
- 9
- Sampling time:
- 56 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- At the conclusion of a 56-day aerobic biodegradability experiment, Reaction products of stearic acid, diethylenetriamine and N-aminoethylethanolamine and acetic acid was determined not to be readily biodegradable (<60 % by day 28) (CLP Regulation (EC) No. 1272/2008).
- Executive summary:
An experiment was undertaken to determine whether Reaction products of stearic acid, diethylenetriamine and N-aminoethylethanolamine and acetic acid, which is a substance of Unknown or Variable Composition, Complex Reaction Products and Biological Materials (UVCB), has the potential to be readily biodegradable under aerobic conditions. A 56-day test was performed according to Good Laboratory Practise (GLP) and OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test) without deviation. Liquid sewage (66 % urban and 34 % industrial) was obtained from a treatment plant for the purpose of the inoculum and a suitable culture medium prepared to be used in the blank (inoculum only), test sample, reference substance (sodium benzoate), and test sample + reference substance treatments. The initial nominal concentration for the test and reference substance was 18.81 and 19.05 mg/L of Total Organic Carbon (TOC), respectively. Total Inorganic Carbon (TIC) was measured on day 0, 1, 7, 14, 21, 28, 35, 42, 49, and 56 to determine percentage biodegradability.
The quality criteria of the experiment were satisfied. Percentage biodegradability on day 28 and at the termination of the experiment (day 56) was found to be 17 and 9 %, respectively. A UVCB substance is regarded as being readily biodegradable when its level of biodegradability is ≥60 % within a 28-day period (CLP Regulation (EC) No. 1272/2008). As the experimentally-derived values for biodegradability were <60 %, Reaction products of stearic acid, diethylenetriamine and N-aminoethylethanolamine and acetic acid was regarded as being non-readily biodegradable under the conditions of the test.
Reference
Description of key information
At the termination of a 56-day aerobic biodegradability experiment undertaken according to OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test), Reaction products of stearic acid, diethylenetriamine and N-aminoethylethanolamine and acetic acid was determined not to be readily biodegradable. Biodegradation of the test item was 17 % on day 28 and 9 % on day 56, the former of which is lower than the threshold of ≥60 % by day 28 specified under CLP Regulation (EC) No. 1272/2008.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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