Registration Dossier
Registration Dossier
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EC number: 236-885-7 | CAS number: 13532-94-0
Endpoint summary
Administrative data
Description of key information
The toxicity to the aquatic environment of 2-Butoxyethyl methacrylate was investigated by performing GLP compliant short-term toxicity studies to freshwater aquatic invertebrates, algae and fish in accordance with Annex VII of REACH.
The concentration of 2-butoxyethyl methacrylate that elicits a 50% response (EC50) from the freshwater algae Pseudokirchneriella subcapitata over 72-hour period was determined to be 17.5 mg/l based on growth rate. The registered substance can subsequently be regarded as not acutely toxic to aquatic algae and cyanobacteria under the conditions of the study given that this value is >1 mg/l (CLP Regulation (EC) No 1272/2008.
A 48-hour EC50, NOEC, and LOEC of 152, 100, and 200 mg/l, respectively, were determined following a 48-hour acute aquatic toxicity experiment in which Daphnia magna were exposed to 2-butoxyethyl methacrylate. As the 48-hour EC50 is greater than 1 mg/l, the registered substance is not considered to be a acutely toxic to aquatic invertebrates (CLP Regulation (EC) No 1272/2008).
Zebra Fish (Danio Rerio) was identified as the most sensitive species based on the outcome of the investigatin with a 96h LC50 of 4.592 mg/l. As the lowest L(E)C50 for 2-Butoxyethyl methacrylate is above 1 mg/l, the substance does NOT meet criteria for classification as Aquatic Acute 1; H400 in accordance with Regulation (EC) N° 1272/2008.
There is no available data on the chronic toxicity of 2 -Butoxyethyl methacrylate to the aquatic environment. As the substance is being registered under REACH in the 1 -10 tonnage band there is no information requirement for long-term studies. Therefore, the classification of the registered substance for chronic effects is based on the short-term toxicity to the aquatic environment and its readily biodegradability. Given that the substance is rapidly degradable, it does not meet the criteria for classification for long lasting effects to the aquatic environment in accordance with the CLP Regulation (EC) N ° 1272/2008
Additional information
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