Registration Dossier
Registration Dossier
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EC number: 216-028-3 | CAS number: 1477-42-5
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 4-methylbenzothiazol-2-ylamine
- EC Number:
- 216-028-3
- EC Name:
- 4-methylbenzothiazol-2-ylamine
- Cas Number:
- 1477-42-5
- Molecular formula:
- C8H8N2S
- IUPAC Name:
- 4-methyl-1,3-benzothiazol-2-amine
- Test material form:
- solid: particulate/powder
1
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- >= 0.981 - <= 1.65
- Temp.:
- 25 °C
- pH:
- 7.2
Applicant's summary and conclusion
- Conclusions:
- The study was conducted under GLP according to OECD Guideline 117 on the registered substance itself. The method is to be considered scientifically reasonable with no deficiencies in documentation or any deviations and therefore reliability of Klimisch 1 has been assigned. Log Pow has been determined to be 0.981 to 1.65.
- Executive summary:
Pow 9.57 to 44.0, log Pow 0.981 to 1.65, using the HPLC method, designed to be compatible with EU Method A.8 and OECD Guideline 117 (GLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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