Registration Dossier
Registration Dossier
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EC number: 223-804-5 | CAS number: 4079-68-9
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-Finding Toxicity Data: List VIII
- Author:
- Carpenter CP, Weil CR and Smyth HF JR.
- Year:
- 1 974
- Bibliographic source:
- Toxicol. Appl. Pharmacol. 28, 313-319
Materials and methods
- Principles of method if other than guideline:
- Principles of experimental methods according to Smyth and Carpenter (1944, 1948); Smyth et al. 1949, 1951, 1954, 1962, 1969).
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- N,N-diethyl-2-propynylamine
- EC Number:
- 223-804-5
- EC Name:
- N,N-diethyl-2-propynylamine
- Cas Number:
- 4079-68-9
- Molecular formula:
- C7H13N
- IUPAC Name:
- diethyl(prop-2-yn-1-yl)amine
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- LD50
- Effect level:
- 460 mg/kg bw
- Remarks on result:
- other: Original information: LD50 = 570 µL/kg
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
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