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EC number: 201-851-2 | CAS number: 88-68-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96-h LC50 is 395 mg/L in fish (P. promelas).
Key value for chemical safety assessment
Additional information
The short-term toxicity to fish was examined in two studies.
In the first study groups of 20 fish (P. promelas) were exposed to nominal test concentrations of 0 (control), 184, 283, 436, 670 and 1030 mg/L under static conditions for 96 hours (Brooke et al, 1984). Test concentrations were analytically verified on a daily basis. Average analytical test concentrations were <5, 199, 275, 401, 631 and 920 mg/L. Fish were examined for deaths and general symptoms at regular intervals. Deaths and symptoms were observed at all tested concentrations (except controls) and showed a clear concentration dependence. The percentage of death first exceeded 50% (11/20 animals) at a nominal test concentration of 436 mg/L. Based on these findings the 96 -h LC50 was determined at 395 mg/L (based on nominal test concentrations).
In the second study, which was performed in accordance with DIN 38 412, groups of 10 fish (L. idus) were exposed to the substance at nominal test concentrations of 0 (control), 100, 215, 464 and 1000 mg/L under static conditions for 96 hours (BASF, 1990). No analytical verification of test concentrations was performed. Fish were examined for deaths and general symptoms at regular intervals. At a test concentration of 1000 mg/L all fish died after 24 hours of exposure. No deaths were observed at any of the other concentrations tested. Based on the findings, the 96 -h LC50 value was determined at >464 mg/L.
As both studies are considered to be of equal quality, the lowest effect value of 395 mg/L is used for assessment.
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