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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
test substance eluted as three peaks using the HPLC method and the mean offset adjusted Log Pow for the test substance by UV ranged from unretained (< -1.02) to 4.65 (OECD 117, EU Method A.8 and OPPTS 830.7570).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.65
- at the temperature of:
- 40 °C
Additional information
GUIDELINE
The study was conducted using High Performance Liquid Chromatography (HPLC) and procedures in the U.S. EPA Product Properties Test Guidelines, OPPTS 830.7570,Partition Coefficient (n-Octanol/Water), Estimation by LiquidChromatography, OECD Guideline for the Testing of Chemicals, 117, Partition Coefficient(n-octanol/water), High Performance Liquid Chromatography (HPLC) Method, Official Journal of the European Communities No. L383 Method A.8: Partition Coefficient(3) and TSCA Title 40 of the Federal Code of Regulations, Part 796, Section 1570: Partition Coefficient (n-Octanol/Water).
METHODS
Three solutions of test material were prepared in 75% methanol (MeOH): 25% reagent water (H2O) v/v at a nominal concentration of 1.00 mg/mL. Each test substance solution was prepared from the appropriate stock solution in MeOH. Seven calibration reference standards, consisting of seven reference substances of known log Pow, were prepared in the respective mobile phase at a nominal concentration range (5.00 to 50.0 mg/L) selected to provide desired ultraviolet (UV) detector response. The calibration reference standard preparations were sequentially injected into an HPLC system followed by single injections of each test substance preparation. The calibration reference standards injection sequence was repeated following the test substance injections. The HPLC system was operated under standardised isocratic, reverse-phase operating conditions per the guideline.
RESULTS
The test substance eluted as three peaks using the HPLC method and the mean offset adjusted Log Pow for the test substance by UV ranged from unretained (< -1.02) to 4.65.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.