Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 275-640-9 | CAS number: 71566-55-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988-07-18 - 1988-08-04
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- (1984)
- Deviations:
- yes
- Remarks:
- Highest vehicle concentration: 791.4 mg/L
- GLP compliance:
- no
Test material
- Reference substance name:
- 9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium bis[3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-4-hydroxy-N-3-(isopropoxypropyl)benzenesulphonamidato(2-)]cobaltate(1-)
- EC Number:
- 275-640-9
- EC Name:
- 9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium bis[3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-4-hydroxy-N-3-(isopropoxypropyl)benzenesulphonamidato(2-)]cobaltate(1-)
- Cas Number:
- 71566-55-7
- Molecular formula:
- C44H50CoN10O10S2.C28H31N2O3
- IUPAC Name:
- 9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthylium bis[3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-4-hydroxy-N-3-(isopropoxypropyl)benzenesulphonamidato(2-)]cobaltate(1-)
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Physical state: powder (solid)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- stock solution: 5.0 g test item and 20.0 mg alkylphenol-polyglykol-ether were mixed with and made up to 50 mL with acetone.
- Controls:
Blank: Dechlorinated tap water (carbon filter)
Vehicle: Dechlorinated tap water with the vehicle
- Chemical name of vehicle: Acetone and alkylphenol-polykol-ether
- Concentration of vehicle in test medium: 791 mg acetone and 0.4 mg alkylphenol-polyglykol-ether per liter water in the concentration used for the highest test concentration.
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: Zebrafish
- Length: 21 mm (15-25 mm)
- Weight: 0.11 (0.02-0.20g)
- Source: West Aquarium, Bad Lauterberg, Germany
- Feeding during test: None
ACCLIMATION
- Acclimation period: 19 days
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 164 mg CaCO3/L
- Test temperature:
- 22-24 °C
- pH:
- 8.0-8.3
- Dissolved oxygen:
- O2%: 90-102
- Nominal and measured concentrations:
- Nominal concentrations: 10, 18, 32, 58, 100 mg/L;
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 L glass aquaria
- Material, fill volume: Glass aquaria filled with 15 L
- No. of organisms: 10 fishes per concentration and control, 10 fishes per aquarium
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - No abnormal responses of the fish were observed.
- No mortality of the fish were observed.
Any other information on results incl. tables
- Sublethal observations / clinical signs:
measurement start 24h 48h 72h 96h blank dead/alive 0/10 0/10 0/10 0/10 0/10 oxygen % 102 95 93 90 91 pH 8.0 8.1 8.3 8.3 8.3 temperature °C 22 22 23 23 23 Vehicle dead/alive 0/10 0/10 0/10 0/10 0/10 oxygen % 101 91 91 90 90 pH 8.2 8.2 8.2 8.2 8.2 temperature °C 23 23 23 23 23 10 mg/L dead/alive 0/10 0/10 0/10 0/10 0/10 oxygene % 102 92 91 90 90 pH 8.0 8.2 8.2 8.2 8.2 temperature °C 22 23 23 23 23 18 mg/L dead/alive 0/10 0/10 0/10 0/10 0/10 oxygen % 101 99 98 96 92 pH 8.1 8.1 8.2 8.2 8.2 temperature °C 22 23 23 23 23 32 mg/L dead/alive 0/10 0/10 0/10 0/10 0/10 oxygene % 102 94 96 94 92 pH 8.1 8.2 8.3 8.3 8.3 temperature °C 22 23 23 23 23 58 mg/L dead/alive 0/10 0/10 0/10 0/10 0/10 oxygen % 102 99 96 94 92 pH 8.0 8.2 8.2 8.2 8.2 temperature °C 22 23 23 23 23 100 mg/L dead/alive 0/10 0/10 0/10 0/10 0/10 oxygen % 102 96 93 92 90 pH 8.1 8.1 8.2 8.2 8.2 temperature °C 22 22 23 23 23
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test substance is with high probability not acutely harmful to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
