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Diss Factsheets
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EC number: 612-032-8 | CAS number: 6080-58-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: According to OECD SIDS Initial Assessment Report (2001)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- not specified
- Inoculum or test system:
- other: sewage treatment
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Remarks on result:
- not measured/tested
- Key result
- Parameter:
- BOD5*100/ThOD
- Value:
- ca. 58 - ca. 61 other: %
- Remarks on result:
- other: data from three publications
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In the OECD SIDS Initial Assessment Report for citric acid a BOD5/ThOD of 58 - 61% based on the results of three Closed Bottle tests is reported.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According to OECD SIDS Initial Assessment Report (2001)
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449/EEC, C.5 „Biotic degradation – modified Sturm test“
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: sewage treatment, non-adapted
- Duration of test (contact time):
- 28 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 97
- Sampling time:
- 28 d
- Remarks on result:
- other: no standard deviation given
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 28 d
- Remarks on result:
- other: no standard deviation given
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- In the OECD SIDS Initial Assessment Report for citric acid 97% degradation based on CO2 evolution in a Modified Sturm test is reported. Thus, the substance is considered to be readily biodegradable.
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According to OECD SIDS Initial Assessment Report (2001)
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 87/302/EEC, part C, p. 99 "Biodegradation: Zahn-Wellens test"
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: sewage treatment
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 85
- Sampling time:
- 1 d
- Remarks on result:
- other: no standard deviation given
- Conclusions:
- In the OECD SIDS Initial Assessment Report for citric acid 85% degradation after 1 day based on DOC removal in a Zahn-Wellens test is reported.
Referenceopen allclose all
Description of key information
In the aquatic compartment, citric acid is expected to be rapidly degraded based on the results from several ready and inherent aerobic biodegradation tests. Since citric acid is formed by the reaction of lithium citrate or lihtium citrate tetrahydrate with water, read-across with citric acid is considered as reasonable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Lithium citrate and lithium citrate tetrahydrate completely dissociates in water forming lithium hydroxide and citric acid. Thus, citric acid was found to be a suitable candidate for read-across.
Based on several ready and inherent aerobic degradation tests, citric acid is expected to be rapidly degradable in the aquatic compartment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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