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EC number: 309-831-6 | CAS number: 101227-08-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005-01-13 - 2005-02-11
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 301 B
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
The CO2-free air production system consisted of an air compressor, two 1000 ml gas wash bottles filled with dry soda lime, followed by one bottle filled with 0.1 M NaOH (sodium hydroxide) and one gas wash bottle filled with demineralised water. The CO2-free air was passed on to an air distributewith two input and 22 output channels and through PE-tubes. Gas wash bottles (2000 ml volume) with lateral connecting pieces for butyl rubber septums were used as reactors. The liquid volume was fixed as 1.500 ml each. Mixing was performed by a magnetic stirrer with 2 cm stir bars. 43.4 µl of the test item were added into the three test vessels and the vessel for toxicity control, corresponding to a TOC concentration of 20 mg/l TOC. From the reference compound 5.15 ml of a stock solution of 10 g/l were added to the reference vessels and the vessels for toxicity control. The CO2 produced in the reactors was absorbed in two 250 ml gas wash bottles in series, each filled with 200 ml 0.2 M NaOH. Sampling was performed through the lateral connecting pieces through the butyl rubber septum using 5 ml PE syringes. The amount of CO2 released from the reactors is calculated through IC-measurements in the CO2-absorber while considering the amount of CO2 removed for IC-measurement. - Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- Activated sludge from the municipal wastewater treatment plant Breisgauer Bucht was used as inoculum with a concentration corresponding to 30 mg dry solids per litre. The treatment plant clarifies predominantly domestic wastewater of the region of Freiburg and has a capacity of 600.000 inhabitant equivalents. Sampling date of activated sludge was January 11th, 2005. Dry solids of the activated sludge was determined as 5.4 g/l by weight measurements after 2 h drying at 105°C (mean of triplicate measurements). The activated sludge was washed twice by settling the sludge, decanting the supernatant and re-suspending the sludge in aerated tap water.
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 28 d
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 24.86 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- 20 mg/L organic carbon, Organic carbon in the test substance 80.45 %
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 20 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: organic carbon
- Validity criteria fulfilled:
- yes
- Conclusions:
- The degradation in the toxicity control was 75.8% within 14 days and 93.8% within 28 days (after acidification), so there was no inhibition of the inoculum caused by the test item.
- Executive summary:
The degradation in the toxicity control was 75.8% within 14 days and 93.8% within 28 days (after acidification), so there was no inhibition of the inoculum caused by the test item.
In the Toxicity control 5.15 ml of a stock solution of 10 g/l reference substance and 43.4 µl of the stock solution of the test item were added into the vessel. This correspondens to 40 mg/L organic carbon.
43.4 µl stock solution correspondens to 20 mg/L organic carbon. The test substance contains 80.45 % Organic Carbon. That means that 24.86 mg/L test substance does not have effects on activated sludge. Activated sludge was used as inoculum with a concentration corresponding to 30 mg dry solids per litre.
Reference
Description of key information
In the biodegradation test no inhibition of the inoculum caused by the target substance Fatty acids, C16-18, 2-butyloctyl esters was found.
in that study 24.86 mg/L test substance does not have effects on activated sludge.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 24.86 mg/L
Additional information
The degradation in the toxicity control of an OECD 301B test performed with the test substance, Fatty acids, C16-18, 2-butyloctyl esters achieved 75.8% within 14 days and 93.8% within 28 days (after acidification), so there was no inhibition of the inoculum caused by the test item. In the Toxicity control 5.15 ml of a stock solution of 10 g/l reference substance and 43.4 µl of the stock solution of the test item were added into the vessel. This corresponds 40 mg/L organic carbon. 43.4 µl stock solution corresponds to 20 mg/L organic carbon. The test substance contains 80.45 % Organic Carbon. That means that 24.86 mg/L test substance does not have effects on activated sludge. Activated sludge was used as inoculum with a concentration corresponding to 30 mg dry solids per litre.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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