Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 273-224-1 | CAS number: 68953-70-8 The complex combination of alkanolamines from the distillation of reaction products of ammonia and oxirane. It consists predominantly of triethanolamine, diethanolamine and higher amines from the reaction of triethanolamine and oxirane.
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when the substance is introduced in appropriately low concentrations.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 20.6 mg/L
- EC10 or NOEC for microorganisms:
- 171 mg/L
Additional information
The effect of AMIX TE (Oxirane, reaction products with ammonia, distn. residues; CAS 68953 -70 -8) on the growth of microorganisms was studied in a GLP test following the procedures of the German Industrial Standard DIN guideline 38412. Pseudomonas putida was used as test species. Test concentrations ranged between 39 and 10000 mg/L were applied. Two concentrations were also tested after neutralisation (1250 and 10000 mg/L). After 16 h the EC10 was determined to be 171 mg/L, the EC50 was 20.6 mg/L (nominal; BASF 1996, project no. 95/067/70/2). The growth inhibiting effect was lower in the neutralised test samples indicating that part of the toxicity of the test substance is due to the high pH. It can be concluded that the inhibition of the degradation activity of activated sludge is not anticipated when the substance (AMIX TE) is introduced in appropriately low concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
