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EC number: 223-296-5 | CAS number: 3811-73-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in air
Administrative data
- Endpoint:
- phototransformation in air
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
- Principles of method if other than guideline:
- Not applicable; model calculation according to the Atkinson calculation method.
- GLP compliance:
- no
- Remarks:
- Not relevant
Test material
- Reference substance name:
- Pyridine-2-thiol 1-oxide, sodium salt
- EC Number:
- 223-296-5
- EC Name:
- Pyridine-2-thiol 1-oxide, sodium salt
- Cas Number:
- 3811-73-2
- Molecular formula:
- C5H5NOS.Na
- IUPAC Name:
- sodium (1-oxo-1λ⁵-pyridin-2-yl)sulfanide
Constituent 1
Study design
- Estimation method (if used):
- -Atkinson calculation method
-AOPWIN (Atmospheric Oxidation Program v1.91
Results and discussion
Any other information on results incl. tables
The total OH radical reaction rate constant (kOH) is given by:
kOH= k (H-atom abstraction from C-H and O-H bonds)
+ k (OH radical addition to aromatic rings)
+ k (OH radical addition to fused rings)
+ k (OH radical interaction with N-, S- and OH-containing groups)
For Sodium pyrithione kOHis:
kOH= k (H-atom abstraction from C-H and O-H bonds) + k (OH radical interaction with N-, S- and OH-containing groups) + k (OH radical addition to aromatic rings) + k (OH radical addition to fused rings)
The hydrogen abstraction (H-atom abstraction from C-H bonds) has a value of
k = 0.0000 cm3molecule-1sec-1(no hydrogen abstraction).
The OH radical interaction with N- and OH-containing groups has a value of
k = 0.0000 × 10-12cm3molecule-1sec-1(aromatic nitrogen).
The OH radical addition to aromatic rings has a value of
k = 2.3854 × 10-12cm3molecule-1sec-1
The OH radical addition to fused rings has a value of
k = 0.000 × 10-12cm3molecule-1sec-1
The overall OH rate constant is estimated to be:
kOH= 2.3854 × 10-12cm3molecule-1sec-1.
The tropospherical half life is calculated from the overall OH radical reaction rate constant using the equation:
t1/2 = ln2/KOH x [OH]
[OH] = the model default OH radical concentration in the troposphere of 1.5 x 106molecule-cm3(12 hours irradiation per day).
For zinc pyrithione the calculated tropospherical half life is:
0.693/(2.3854E-12 x 1.5E6) = 193678 seconds = 53.8 hours
Applicant's summary and conclusion
- Conclusions:
- Sodium pyrithione degrades quickly in the atmosphere by reaction with OH radicals, having a half life of 53.8 hours. Considering that sodium pyrithione is non-volatile (vapour pressure <4.6 x 10exp-5 Pa), significant pollution of the air by the use of sodium pyrithione can be excluded. The information contained within this robust summary document comes from studies which are in the ownership of Arch Chemicals Inc. and which are protected in several regions globally. This information may not be used for any purpose other than in support of the Chemical safety Report submitted by Arch Chemicals Inc. under Regulation EC 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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