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EC number: 298-078-6 | CAS number: 93777-46-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Skin irritation (OECD 439): not irritating
Eye irritation (similar to OECD 492): not irritating
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin Irritation (in vitro)
CAS 93777-46-9
The skin irritation properties of Decyl 2-Ethylhexanoatewere tested in a study according to OECD 439 and EU Method B.46 and in compliance with GLP (Eurlings, 2016). The EPISKIN Small Model™ was exposed to 25 μL of the unchanged test material for 15 ± 0.5 minutes and was incubated for another 42 hours after one washing step. The MTT test revealed a mean tissue viability of 102%. Therefore, Decyl 2-Ethylhexanoate is not regarded as skin irritant.
Eye irritation (in vitro)
CAS 93777-46-9
The eye irritation properties of Decyl 2-Ethylhexanoatewere tested in a study according to OECD 492 and in compliance with GLP (Eurlings, 2015). The EpiOcular™ cornea epithelial model was exposed to 50 μL of the neat/ undiluted test material for 30 ± 2 minutes and was incubated for another 2 hours after rinsing and removal of the test item. The MTT test revealed a mean tissue viability of 88%. Based on the obtained results, Decyl 2-Ethylhexanoate is not eye irritating.
Conclusion on skin and eye irritation properties
The available data on skin irritation with Decyl 2-Ethylhexanoate (CAS 93777-46-9) do not meet the criteria for classification according to Regulation (EC) No 1272/2008, as the classification criteria according to OECD 437 were not met (< 50% of the mean viability of the negative control) and are therefore conclusive but not sufficient for classification.
The available data on eye irritation with Decyl 2-Ethylhexanoate (CAS 93777-46-9) do not meet the criteria for classification according to Regulation (EC) No 1272/2008, as the classification criteria according to OECD 492 were not met (< 50% of the mean viability of the negative control) and are therefore conclusive but not sufficient for classification.
Justification for classification or non-classification
The available data on irritation do not meet the classification criteria according to Regulation (EC) 1272/2008, and are therefore conclusive but not sufficient for classification.
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