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EC number: 267-500-0 | CAS number: 67874-72-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Coniferan biodegrades up to 12% in an OECD TG 310 study and is considered non-readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
Additional information
The key study is a screening study according to OECD TG 310 (Headspace Test) and in compliance with GLP criteria (WIL, 2012). In this study an amount of 20 mg/L test substance (expressed as TOC) was inoculated with non-adapted activated sludge from a domestic sewage treatment plant for 28 days. CO2 evolution from the ultimate aerobic biodegradation of the test substance is determined by measuring the inorganic carbon (IC) produced in the test bottles over that produced in the blank control bottles. The amount of IC produced by the test substance (corrected for that evolved by the controls and the amount added by basification, where applicable) is expressed as a percentage of the theoretical amount of IC (ThIC) that could have been produced if complete biodegradation of the test substance occurred. The study contained two tests. The initial test was a standard ready biodegradability test conducted according to OECD 310 Guidelines. The second test was an enhanced biodegradation screening test, also based upon OECD 310 Guidelines. The enhancements included low-level pre-adaptation, by utilization of inoculum pre-exposed to the test substance concurrently with the conduct of the first test and by extending the test duration to 60 days. Each test contained a blank control group, two reference groups and a treatment group. The blank controls were used to measure the background IC production of the inoculum medium and were not dosed with a carbon source. The reference chambers were dosed with either rapeseed oil or 1 -Octanol, substances known to be biodegradable, at a nominal concentration of 20 mg C/L. The results indicated that the activated sludge inoculum was active, degrading the reference substances rapeseed oil and 1 -Octanol respectively 81.5% and 74.2% in the initial test with a 28-day duration and 61.6% and 72.3% by day 28 in the second test with a 60-day duration. The average cumulative percent biodegradation for the test substance was 12.4% in the initial test and 17.1% in the second test.
In a supporting study, the non ready biodegradability is confirmed. In this study, also a headspace test performed according to OECD TG 310, Coniferan was biodegradaded 3% after 28 days and 1% after 56 days inoculation (van Ginkel and Geerts, 2008). The study report provides a bit less detail on study results but is nonetheless considered to be reliability 2 and thus adequate to support the key value for chemical safety assessment.
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