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Diss Factsheets
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EC number: 807-276-9 | CAS number: 1421695-64-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Chemicals-Adsorption-Desorption Using a Batch Equilibrium Method (GB/T21851-2008)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.18 (Adsorption / Desorption Using a Batch Equilibrium Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: The Guidelines for the Testing of Chemicals, Physico-Chemical Properties and Physical Hazards (the 2nd edition). Beijing: China Environmental Press
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
Test material
- Test material form:
- liquid
- Details on test material:
- - Purity: >99%
Constituent 1
- Radiolabelling:
- no
Study design
HPLC method
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: UPLC ACQUITY
- Column: 1.8 µm 2.1 x 100 mm Column
- Detection system: ACQUITY UPLC PDA Detector
- Wavelength : 210 nm
- Column temperature: 30°C
- Mobile phase: Acetonitrile: 0.1 % formic acid: 55:45
- Flow rate: 0.3 mL/min
- Inject volume: 10 µL
- Retention time: 1.9 min
Batch equilibrium or other method
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 0.50, 1.00, 2.00, 5.00, 10.0 and 20.0 mg/L
- Sample storage before analysis: Room temperature
Results and discussion
Adsorption coefficientopen allclose all
- Key result
- Sample No.:
- #1
- Type:
- Kd
- Value:
- 27.3 other: cm3/g
- Key result
- Sample No.:
- #2
- Type:
- Kd
- Value:
- 21.6 other: cm3/g
- Key result
- Sample No.:
- #3
- Type:
- Kd
- Value:
- 96 other: cm3/g
- Key result
- Sample No.:
- #4
- Type:
- Kd
- Value:
- 20.1 other: cm3/g
- Key result
- Sample No.:
- #5
- Type:
- Kd
- Value:
- 53.4 other: cm3/g
- Key result
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 417 other: cm3/g
- Key result
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 1 597 other: cm3/g
- Key result
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 1 792 other: cm3/g
- Key result
- Sample No.:
- #4
- Type:
- Koc
- Value:
- 1 448 other: cm3/g
- Key result
- Sample No.:
- #5
- Type:
- Koc
- Value:
- 780.2 other: cm3/g
Results: Batch equilibrium or other method
- Adsorption and desorption constants:
- The results of adsorption kinetic experiments show that the adsorption coefficient (Kd) values of test substance in A, B, C, D, E soil were 27.3, 21.6, 96.0, 20.1 and 53.4 cm3/g, respectively. And the Koc values of test substance were 417.0, 1597, 1792, 1448 and 780.2 cm3/g, respectively.
The results of desorption kinetic experiments show that during the appropriate desorption equilibrium time of 48 h, the test substance was not detected in the supernatant of A B, C, D, E soil
The results of adsorption isotherms experiments show the Freundlich adsorption coefficient values in five soils were 154, 148, 227, 113 and 213, respectively. The 1/n value for different soils was 0.269-0.365.
The results of desorption isotherms experiments show that during the appropriate desorption equilibrium time of 48 h, the test substance was not detected in the supernatant of A, B, C, D, E soil.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Adsorption coefficient (Kd): 27.3, 21.6, 96.0, 20.1 and 53.4 cm3/g; Koc: 417.0, 1597, 1792, 1448 and 780.2 cm3/g.
Test substance was not detected in the supernatant of different type of soil for desorption. - Executive summary:
According to "The guidelines for the testing of chemicals" (HJ/T 153-2004) and "The Guidelines for the Testing of Chemicals-Physical-Chemical Properties and Physical Hazards" (the 2nd edition. Beijing: China Environment Press. 2013), with reference to Procedure 106 of the "Guidelines for Testing of Chemicals" of the OECD: "Adsorption-Desorption Using a Batch Equilibrium Method" (2000), the adsorption-desorption test for test substance was conducted for generating essential information of biogeocoenosis for new chemicals registration. Five soil types with different pH, texture, and organic carbon contents sampling from Jilin, Jiangxi, Jiangsu, Shandong and Gansu provinces of China were selected. Batch equilibrium method was adopted, and tests were performed to determine the adsorption characteristics of test substance.
The results show that optimal soil/aqueous ratio for the five soils were 1:100, and the appropriate adsorption equilibrium time was 24 h.
The results of adsorption kinetic experiments show that the adsorption coefficient (Kd) values of test substance in A, B, C, D, E soil were 27.3, 21.6, 96.0, 20.1 and 53.4 cm3/g, respectively. And the Koc values of test substance were 417.0, 1597, 1792, 1448 and 780.2 cm3/g in above soils respectively.
The results of desorption kinetic experiments show that during the appropriate desorption equilibrium time of 48 h, the test substance was not detected in the supernatant of A B, C, D, E soil.
The results of adsorption isotherms experiments show the Freundlich adsorption coefficient values in five soils were 154, 148, 227, 113 and 213, respectively. The 1/n value for different soils was 0.269-0.365.
The results of desorption isotherms experiments show that during the appropriate desorption equilibrium time of 48 h, the test substance was not detected in the supernatant of A, B, C, D, E soil.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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