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Diss Factsheets
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EC number: 267-032-7 | CAS number: 67762-73-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 12 January 2016 to 10 February 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- Slow stir adaptation of the shake flask test method.
- GLP compliance:
- no
- Remarks:
- Non-GLP study performed by a GLP accredited lab.
- Type of method:
- flask method
- Water solubility:
- < 23 mg/L
- Temp.:
- 25 °C
- pH:
- 6.14
- Remarks on result:
- other: Mean results at day 1, 0.1% concentration
- Water solubility:
- 31 mg/L
- Temp.:
- 25 °C
- pH:
- 5.3
- Remarks on result:
- other: Mean results at day 3, 0.1% concentration
- Water solubility:
- 48 mg/L
- Temp.:
- 25 °C
- pH:
- 4.77
- Remarks on result:
- other: Mean results at day 7, 0.1% concentration
- Water solubility:
- 44 mg/L
- Temp.:
- 25 °C
- pH:
- 5.18
- Remarks on result:
- other: Mean results at day 1, 0.5% concentration
- Water solubility:
- 116 mg/L
- Temp.:
- 25 °C
- pH:
- 3.92
- Remarks on result:
- other: Mean results at day 3, 0.5% concentration
- Water solubility:
- 162 mg/L
- Temp.:
- 25 °C
- pH:
- 3.68
- Remarks on result:
- other: Mean results at day 7, 0.5% concentration
- Conclusions:
- Due to the variation observed during this study, it was not possible to derive a definitive value for the water solubility of the registered substance.
- Executive summary:
When tested according to OECD Guideline 105, it was not possible to derive a definitive value for the water solubility of the registered substance. The water solubility will depend of the loading and of the duration of the study. The values ranged from <23 mg/L (day 1, 0.1 % concentration) to 162 mg/L (day 7, 0.5 % concentration) at 25 °C.
Reference
Total concentration of the test substance for each replicate plus the average and reported concentrations
Test | pH | Total Concentration (mg/L) | Average (mg/L) | Reported Result (mg/L) | |
1 day, 0.1% | 1 | 6.17 | 27.93 | <22.6 | <23 |
2 | 6.11 | <17.20 | |||
3 day, 0.1% | 1 | 5.23 | 32.59 | 30.9 | 31 |
2 | 5.37 | 29.31 | |||
7 day, 0.1% | 1 | 5.04 | 39.48 | 47.8 | 48 |
2 | 4.50 | 56.21 | |||
1 day, 0.5% | 1 | 5.69 | 33.28 | 43.5 | 44 |
2 | 4.68 | 53.79 | |||
3 day, 0.5% |
1 | 3.86 | 134.31 | 116.3 | 116 |
2 | 3.97 | 98.28 | |||
7 day, 0.5% | 1 | 3.67 | 168.28 | 162.1 | 162 |
2 | 3.69 | 155.86 | |||
Water Blank | 6.58 | Not Detected | Not Applicable | Not Applicable |
Description of key information
The study was performed on the registered substance. Depending on the test conditions, the water solubility ranged from <23 mg/L (day 1, 0.1 % concentration) to 162 mg/L (day 7, 0.5 % concentration) at 25 °C.
Key value for chemical safety assessment
Additional information
The water solubility of the registered substance was determined in accordance with the OECD Guideline for Testing of Chemicals 105. The results showed signs of loading and time dependency, and it was not possible to obtain a definitive value regarding the water solubility, which ranged from <23 mg/L (day 1, 0.1 % concentration) to 162 mg/L (day 7, 0.5 % concentration) at 25 °C - and therefore from slightly to moderately soluble - depending on the test conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.