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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from authorative handbook and database

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
DPIM: AJS500
Author:
Richard J. Lewis, Sr.
Year:
2007
Bibliographic source:
SAX (Sax's Handbook of Dangerous Industrial Materials),(Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia.:  , 1972, 192. )
Reference Type:
review article or handbook
Title:
RTECS NUMBER : DB5030000
Author:
RTECS database
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances);(28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 192, 1972

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: as below
Principles of method if other than guideline:
Data is from SAX and RTECS
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Reference substance name:
4-aminoazobenzene-3, 4’-disulphonic acid
IUPAC Name:
4-aminoazobenzene-3, 4’-disulphonic acid
Constituent 2
Chemical structure
Reference substance name:
4-aminoazobenzene-3,4'-disulphonic acid
EC Number:
202-947-7
EC Name:
4-aminoazobenzene-3,4'-disulphonic acid
Cas Number:
101-50-8
Molecular formula:
C12H11N3O6S2
IUPAC Name:
4-aminoazobenzene-3,4'-disulphonic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material: 4-aminoazobenzene-3, 4’-disulphonic acid- Molecular formula: C12H11N3O6S2- Molecular weight: 357.36- Substance type: Organic

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
No data available

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
No data available
Doses:
No data available
No. of animals per sex per dose:
No data available
Control animals:
not specified
Details on study design:
No data available
Statistics:
No data available

Results and discussion

Preliminary study:
No data available
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
14 800 mg/kg bw
Based on:
test mat.
Mortality:
No data available
Clinical signs:
other: No data available
Gross pathology:
No data available
Other findings:
No data available

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated informationCriteria used for interpretation of results: EU
Conclusions:
The Acute oral median Lethal dose (LD50) value of 4-aminoazobenzene-3, 4’-disulphonic acid was found to be 14,800 mg/kg Bw. From this value it is concluded that 4-aminoazobenzene-3, 4’-disulphonic acid does not exhibit acute toxicity by oral route.
Executive summary:

The Acute oral median Lethal dose (LD50) value of 4-aminoazobenzene-3, 4’-disulphonic acid was found to be 14,800 mg/kg Bw. From this value it is concluded that 4-aminoazobenzene-3, 4’-disulphonic acid does not exhibit acute toxicity by oral route.