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Diss Factsheets
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EC number: 255-255-2 | CAS number: 41198-08-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, adapted
- Details on inoculum:
- Obtained from local municiple waste water treatment plant. Sludge was seived (2mm) and concentrated by centrifugation and supernatant discarded. Sludge washed with mineral medium, centrifuged and supernatant discarded. Moisture content of sludge determined by drying. A sludge sloution containing 4.0g solids/L mineral medium prepared one day prior to test initiation. Inoculum solution stored in an environmental chamber under aeration.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 108.5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 134.89 mg/L
- Based on:
- ThOD/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- 7 vessels were set up: 2 test suspension vessels, 2 inoculum blank vessels, 1 procedural control, 1 abiotic sterile control (no inoculum), 1 toxicity control.
- Reference substance:
- other: Sodium benzoate
- Test performance:
- BOD in inoculum blanks were 47.8 and 50.6 mg O2/L at 28 days (for valididty should not exceed 60 mg/L) so validity fulfilled. Difference in blanks did not exceed 5% at any timepoint.Rapid degradation of sodium benzoate confirmed presence of an active microbial population and system integrity. Toxicity control compared to procedural control. 95.2% degradation was observed so the test item was not inhibitory to the inoculum.The abiotic sterile control showed neither degradation nor adsorption to the reaction vessel.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 8.4
- Sampling time:
- 28 d
- Details on results:
- Difference between the two replicates was 2% at test completion.
- Results with reference substance:
- 61.6% in 4 days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Since less than 10% degradation was observed for Profenofos at 28 days, Profenofos cannot be classified as readily biodegradable under the conditions of this test.
- Executive summary:
The ready biodegradability of profenofos was carried out to OECD 301F at 22 +/- 1 degree C.
All the validity criteria was fulfilled.
Less than 10% degradation was observed at 28 days. Therefore profenofos cannot be classified as readily biodegradable under the conditions of the test.
Reference
Description of key information
Less than 10% degradation was observed at 28 days. Therefore profenofos cannot be classified as readily biodegradable under the conditions of the test.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The ready biodegradability of profenofos was carried out to OECD 301F at 22 +/- 1 degree C.
All the validity criteria was fulfilled.
Less than 10% degradation was observed at 28 days. Therefore profenofos cannot be classified as readily biodegradable under the conditions of the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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