m-tolylidene diisocyanate

Guidance on Safe Use

First-aid measures

General Advice: First-aid responders should wear protective gloves and in case of spillages respiratory protection. Remove victims from danger zone. Remove contaminated clothing immediately.

Remove contaminated clothing immediately and clean before re-use or dispose it if necessary.

If inhaled: Keep patient calm, remove to fresh air, seek medical attention.

On skin contact: After contact with skin, wash immediately with plenty of water. Consult a doctor if skin irritation persists.

On contact with eyes: Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open, consult an eye specialist.

On ingestion: Immediately rinse mouth and then drink plenty of water, do not induce vomiting, seek medical attention.

Indication of any immediate medical attention and special treatment needed

Treatment: Treat according to symptoms (decontamination, vital functions), no known specific antidote, administer corticosteroid dose aerosol to prevent pulmonary odema.

Note to the physician:

Breathing difficulties may appear with several hours delay. Administer corticosteroid dose aerosol to prevent pulmonary edema. Treat according to symptoms. No specific antidote known.

Most important symptoms and effects may be delayed:  tightness in the chest, coughing, difficulty breathing.

Fire-fighting measures

Suitable extinguishing media: dry extinguishng media, carbon dioxide, alcohol-resistant foam, water spray.

Special hazards arising from the substance or mixture might be carbon monoxide, carbon dioxide, hydrogen cyanide; hydrocyanic acid, nitrogen oxides or isocyanates. The substances/groups of substances mentioned can be released in case of fire.

Advice for fire-fighters

Special protective equipment: wear self-contained breathing apparatus and chemical-specific clothing.

Further information: Keep containers cool by spraying with water if exposed to fire. Dispose of fire debris and contaminated extinguishing water in accordance with official regulations.

Accidental release measures

Personal precautions:

Wear personal protective equipment including breathiong apparatus. Ensure good ventilation.

Prevent material from entering drains/gutters. Cover spilled material with extinguishing foam, if available. Add chemical absorbant or sand, shovel into buckets. Do not close buckets tightly as slow decomposition of the material releases carbon dioxide: danger of pressure buil-up! Dispose of as hazardous waste in accordance with regulations.

Neutralization: mix with a solution of 5-10 % sodium carbonate, 0.2-2 % detergent and 90-95 % of water. Stirr the mixture gently several times a day. Reaction progresses over 5-7 days at temperatures not below 20 °C.

Remark: Do use aprotic polar solvents (meeting the IUPAC definition) for cleaning up only with care, since it may lead to formation of hazardous primary aromatic amine (>0,1%). We use advice against all cleaning operations using aprotic polar solvents within widespread uses by professional workers.  

Handling and storage

Provide suitable exhaust ventilation at the processing machines. Ensure thorough ventilation of stores and work areas. Avoid aerosol formation. When handling heated product, vapours of the product should be ventilated, and respiratory protection used. Wear respiratory protection when spraying. Danger of bursting when sealed gastight. Protect against moisture. Clean up contamination as soon as they occur. Provide basic employee training to prevent/minimize exposures. Products freshly manufactured from isocyanates can contain incompletely reacted isocyanates and other dangerous substances, e.g. primary aromatic amines. Industrial cleaning with aprotic polar solvents (meeting the IUPAC definition) may lead to formation of hazardous primary aromatic amine (>0,1%).

Completely cured polyurethanes (24 h after production) can generally be handled without PPE.

Keep away from water. Segregate from foods and animal feeds. Segregate from acids and bases.

Suitable materials for containers: Stainless steel 1.4301 (V2), Stainless steel 1.4401, Carbon steel (Iron), tinned carbon steel (Tinplate)

Further information on storage conditions: Keep container tightly closed in a cool, well-ventilated place. Protect against moisture. Formation of CO2 and build up of pressure possible. Danger of bursting when sealed gastight. Information concerning the compliance to the Packaging (Essential Requirements) Regulations 1998 and their amendments may be obtained from the manufacturer.

Protect against moisture. If moisture enters isocyanate containers, CO2 forms and pressure builds up.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

2078

Shipping

Labels:

6.1

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

2078

Shipping

Labels:

6.1

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

2078

Shipping information

Proper shipping name and description:

TOLUENE DIISOCYANATE

Labels:

6.1

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

2078

Shipping information

Proper shipping name and description:

TOLUENE DIISOCYANATE

Labels:

6.1

Remarks

SpecialProvisions

Exposure controls / personal protection

Components with workplace control parameters:

CAS-No.: 91-08-7: toluene-2,6-diisocyanate.

TWA value 0.02 mg/m³ (EH40(UK), measured as NCO.

STEL value 0.07 mg/m³ (EH40(UK)),, measured as NCO.

TWA value 0.035 mg/m³ (TRGS 900, Germany)

CAS-No.: 584-84-9: 4-methyl-m-phenylene diisocyanate

TWA value 0.02 mg/m³ (EH40(UK)) measured as NCO.

STEL value 0.07 mg/m³ (EH40(UK)) measured as NCO.

TWA 0.035 mg/m³ (TRGS 900, Germany).

DNEL (worker, inhalation, chronic): 0.035 mg/m³ (sum of isomers)

Personal protective equipment:

respiratory protection:

filter for organic gases with particle filter, at least A2P2 (EN 143 or 149)

hand protection:

Chemical resistant protective gloves (EN 374).

Suitable materials also with prolonged, direct contact (recommended: protective index 6, corresponding > 480 minutes of permeation time according to EN 374):

nitrile rubber (NBR) - 0.4 mm coating thickness

butyl rubber (butyl) - 0.7 mm coating thickness

chloroprene rubber (CR) - 0.5 mm coating thickness.

Unsuitable materials:

polyvinylchloride (PVC) - 0.7 mm coating thickness

Eye protection:

Safety glasses with side-shieleds (frame goggles) (e.g. EN 166)

Body protection:

safety shoes (e.g. according to EN 20346)

General safety and hygiene measures:

Do not breath vapours/spray. With products freshly manufatured from isocyanates body protection and chemical resistant protctive gloves is recommended. Wearing of closed work clothing is required and additionally to the stated personal protective equipent. Keep away from drink, food and animal feeding stuffs. No eating, drinking, smoking or tobacco use at the place of work. Take off immediately all contaminated clothing. Hands and face should be washed before breaks and at the end of shift. At the end of the shift the skin should be cleaned and skin-care agents applied.

Stability and reactivity

Conditions to avoid: temperatures above 40 °C (quality reasons)

Avoid moisture.

Thermal decomposition: 230 °C.

Substances to avoid: copper, zinc, tin, acids, alcohols, amines, water, alkalines, copper alloys, aluminum compounds, strong oxidizing agents.

Hazardous reactions:

On contact with water, carbon dioxide is formed which causes build-up of pressure in tightly closed containers. Risk of bursting. May react violently with ammmonia solution, primary and secondary amines, primary alcohols and hot water.

No hazardous decomposition products if stored and handled as prescribed/indicated.

Disposal considerations

Incinerate in suitable incineration plant, observing local authority regulations.

This product and any uncleaned containers must be disposed of as hazardous waste.

Waste key: 07 02 08

Contaminated packaging:

contaminated packaging should be emptied as far as possible; than it can be passed on for recycling after being thoroughly cleaned.