Registration Dossier
Registration Dossier
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EC number: 204-419-1 | CAS number: 120-71-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature (table)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Guideline:
- other: guideline not specified
- Deviations:
- not applicable
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 6-methoxy-m-toluidine
- EC Number:
- 204-419-1
- EC Name:
- 6-methoxy-m-toluidine
- Cas Number:
- 120-71-8
- Molecular formula:
- C8H11NO
- IUPAC Name:
- 2-methoxy-5-methylaniline
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- 100 mg
- Duration of treatment / exposure:
- 24h
Results and discussion
In vivo
Results
- Irritation parameter:
- other: severity of effect
- Basis:
- mean
- Reversibility:
- not specified
- Remarks on result:
- other: moderate
Applicant's summary and conclusion
- Interpretation of results:
- moderately irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
- Conclusions:
- The test item is moderately irritating to the rabbits eye.
- Executive summary:
The test item is moderately irritating to the rabbits eye.
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