Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-786-5 | CAS number: 7727-54-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1992-09-08 to 1993-04-07
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- other: FIFRA Guideline 72-1 of the Pesticide Assessment Guidelines
- Deviations:
- no
- Principles of method if other than guideline:
- NA
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- Samples were collected form replicate A of the control and treatment exposure at test start and from replicates B of the control and treatment exposure at test end.
- Vehicle:
- no
- Details on test solutions:
- In a range-finding test, the LC50 was determined between 10 and 100 mg/L. Therefore, nominal concentrations were set at 12.96, 21.6, 36, 60 and 100 mg/L.
Measured concentration (mg/L of ammonium persulfate after 0 and 96 h of exposure:
Nominal concentration / 0 h-exposure / 96 h-exposure / % nominal:
0 / ND / ND / NC
12.96 / 11.9 / 12.8 / 96
21.6 / 20.5 / 22.8 / 100
36 / 34.8 / 38.2 / 101
60 / 59.7 / 61.8 / 101
100 / 98.3 / 101.4 / 100 - Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: Rainbow trout
- Source: Mt. Lassen Trout Farm; Red Bluff CA
- Age at study initiation: juveniles
- Length at study initiation: not indicated
- Weight at study initiation: 0.2 to 0.6 g
- Food type: trout chow
ACCLIMATION
- Acclimation period: 22 days at 12 +/- 2 °C in dilution water
- Acclimation conditions (same as test or not): yes
- Type and amount of food: trout chow
- Feeding frequency: not indicated
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- NA
- Hardness:
- 275 mg/L (as CaCO3)
- Test temperature:
- 12.5 - 13.7 °C
- pH:
- 7.9 - 8.4
- Dissolved oxygen:
- 8.3 - 9.7 mg/L
- Salinity:
- 264 mg/L (as CaCO3)
- Nominal and measured concentrations:
- Nominal: 0; 12.96; 21.6; 36; 60; 100 mg/L
Measured: 0; 12.4; 21.7; 36,5; 60.8; 99.9 mg/L - Details on test conditions:
- Toxicity testing was conducted using 25 L glass exposure chambers. The chambers were filled with 10 L of dilution water or test solution. 10 rainbow trouts were impartially distributed to each of the duplicate control and treatment chambers. The test duration was 96 hours during which the organisms were not fed. A daily photoperiod of 16-hours light and 8-hours dark with a 15 to 30 minute dawn/dusk transition, and water temperature of 12 +/- 2 °C were maintained throughout the test. Water quality were measured daily. Average light intensity over the test system was measured at 0 and 96 hours. Temperature of the water bath containing all test chambers was continuously monitored throughout the test. Test organisms were observed daily for mortality and any behavioural changes, and dead test organisms were removed.
- Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 76.3 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % CL: 60.8 to 99.9 mg/L
- Details on results:
- The 96-hour LC 50 of diammonium persulfate for rainbow trout (Oncorhynchus mykiss) was determined to be 76.3 mg/L with a 95 % confidence interval of 60.8 to 99.9 mg/L. A no observed effect concentration (NOEC) could not be determined due to > 10 % mortality at the lowest test concentration.
- Results with reference substance (positive control):
- NA
- Reported statistics and error estimates:
- Statistical analyses based on the measured concentrations of test material. The statistical procedure to be used for calculating the LC50 and 95 % confidence limits was developed by Stephan. A no observed effect concentration (NOEC) will be determined from the highest test concentration causing <= 10 % mortality.
- Sublethal observations / clinical signs:
Table: Mortalities of the rainbow trout (O. mykiss) exposed to ammonium persulfate in a 96 -h static, acute toxicity test:
Mean measured concentration of ammonium persulfate (mg/L)
Cumulative number of dead organisms and percent mortality (parenthetic values)
24h
48 h
72 h
96 h
0 (control)
0 (0)
0 (0)
0 (0)
0 (0)
12.4
0 (0)
0 (0)
6 (30)
6 (30)
21.7
0 (0)
0 (0)
4 (20)
6 (30)
36.5
0 (0)
0 (0)
6 (30)
8 (40)
60.8
0 (0)
0 (0)
1 (5)
2 (10)
99.9
1 (5)
3 (15)
15 (75)
19 (95)
- Validity criteria fulfilled:
- yes
- Conclusions:
- Diammonium persulfate was tested in a acute toxicity to fish study according to FIFRA Guideline 72-1. In this test, the LD50 was determined to be 76.3 mg/L.
- Executive summary:
Diammonium persulfate was tested for acute toxicity to fish in a 96-h static test according to FIFRA Guideline 72-1. The 96-hour LC 50 of diammonium persulfate for rainbow trout, Oncorhynchus mykiss, was determined to be 76.3 mg/L with a 95 % confidence interval of 60.8 to 99.9 mg/L. A no observed effect concentration (NOEC) could not be determined due to > 10 % mortality at the lowest test concentration.
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000-01-31 to 2000-02-04
- Reliability:
- 1 (reliable without restriction)
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- yes
- Remarks:
- ,modified to marine conditions
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Details on sampling:
- The test substance nominal concentrations were prepared as "water-accommodated fractions" according to the OSPAR (1995) guidelines. There was no chemical analytical confirmation of the actual dissolved concentrations.
- Vehicle:
- no
- Details on test solutions:
- A nominal 1000 mg/L solution was prepared in dilution water, shaken vigorously and allowed to stand for one hour. A clear colourless solution obtained. For each nominal concentration the required amount of homogenised sample was added to dilution water.
- Test organisms (species):
- other: Turbot
- Details on test organisms:
- TEST ORGANISM
- Common name: Scophthalmus maximus (Turbot)
- Source: Mannin Sea Farms Ltd.; Derbyhaven, Castletown; Isle of Man
- Length at study initiation: mean length 43.4 mm
- Weight at study initiation: mean weight 2.16 g
ACCLIMATION
- Acclimation period: 24 days - Test type:
- semi-static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- NA
- Hardness:
- NA
- Test temperature:
- 13.5 to 15 °C
- pH:
- 7.9 - 8.2
- Dissolved oxygen:
- 88 to 98 %
- Salinity:
- 36 g/L sodium chloride
- Nominal and measured concentrations:
- nominal. 0: 100; 180, 320; 560; 1000 mg/L
- Details on test conditions:
- The stocks of animals were maintained, and the tests performed, in standardised artificial seawater. Volumes of 10 litres of test solution were prepared in plastic aquaria. A control vessel of 10 litres dilution water was prepared. Seven turbot were placed in each of the test and control vessels. The pH value, dissolved oxygen and temperature were measured on each test and control solution before starting the test. The test and control solutions were replaced every 48 hours up to the maximum exposure period of 96 hours, the remaining live animals being transferred to freshly prepared test solution, and observations of mortality were made daily. The test vessels were maintained at 14 to 16 °C, with a light cycle of 16 hours light and 8 hours dark.
- Reference substance (positive control):
- no
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 203.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % confidence limits: 166.6 to 247.9 mg/L;
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 134 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- 127.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % confidence limits: 114.9 to 142.0 mg/L;
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 107.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95 % confidence limits: 76.9 to 150.7 mg/L;
- Details on results:
- The study revealed a 96 hour LC50 value of 107.6 mg/L and a 24 hour LC50 value of 203.3 mg/L.
- Results with reference substance (positive control):
- NA
- Reported statistics and error estimates:
- Statistics were performed with ToxCalcTM version 5.0; "Comprehensive Toxicity Data Analysis and Database Software"; copyright 1994 - 1996.
- Sublethal observations / clinical signs:
Cumulative percent mortalities:
Exposure period (hours)
Cumulative mortality (%)
Control
100 mg/L
180 mg/L
320 mg/L
560 mg/L
100 mg/L
0
0
0
0
0
0
0
24
0
0
29
100
100
100
48
0
0
100
100
100
100
72
0
14
100
100
100
100
96
0
43
100
100
100
100
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96-hour LC50 was determined to be 107.6 mg/L.
- Executive summary:
Diammonium persulfate was tested in an acute toxicity study to marine water fish in a test according to OECD guideline 203, modified to marine conditions. The determined 96-hour LC50 was 107.6 mg/L.
Referenceopen allclose all
Description of key information
The acute toxicity of the Persulfate Category to fish was tested in four studies. Three studies were available for diammonium persulfate and one for disodium persulfate. The studies were in accordance to FIFRA guideline 72-1 of the pesticide assessment guidelines, OECD guideline 203 and EU Method C.1. The most sensitive LC50 (96 h) value for freshwater was determined at 76.3 mg/L and for marine water at 107.6 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 76.3 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 107.6 mg/L
Additional information
The acute toxicity of the Persulfate Category to fish was tested in four studies. Three studies were available for diammonium persulfate and one for disodium persulfate. For freshwater LC50 (96 h) values ranged from 76.3-163 mg/L. The acute toxicity study to fish with diammonium persulfate according to FIFRA guideline of the Pesticide Assessment revealed a LC50 (96 h) of 76.3 mg/L, the most sensitive value available. For the marine water LC50 (96 h) values ranged from 107.6-323 mg/L. The acute toxicity to marine fish with diammonium persulfate according to OECD guideline 203 revealed a LC50 (96 h) of 107.6 mg/L the most sensitive value available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.